Results 31 to 40 of about 55,527 (114)
International Journal of Oncology, 2017 MicroRNAs (miRNAs) have been reported to play critical roles in tumor progression including hepatocellular carcinoma (HCC). Thus, the underlying mechanisms need further investigation.
Miao Yu +10 more
semanticscholar +1 more source
Journal of Cellular and Molecular Medicine, 2019 Despite initial dramatic efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR‐TKIs) in EGFR‐mutant lung cancer patients, subsequent emergence of acquired resistance is almost inevitable.
Mingzhi Lu +5 more
semanticscholar +1 more source
Biological and Pharmaceutical Bulletin, 2019 Amyloid β protein (Aβ) causes neurotoxicity and cognitive impairment in Alzheimer's disease (AD). Oxidative stress is closely related to the pathogenesis of AD.
M. Iwasaki +5 more
semanticscholar +1 more source
Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
MedComm, Volume 6, Issue 9, September 2025.Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen +4 more
wiley +1 more source
UEG Week 2023 Moderated Posters
, 2023 United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley +1 more source
Scientific Reports, 2018 Kupffer cells (KCs) are key players in maintaining tissue homeostasis and are involved in various liver diseases. However, the roles of KCs in the pathogenesis of cholangiopathy are largely unknown.
Leila Jemail +6 more
semanticscholar +1 more source
Cell Proliferation, Volume 58, Issue 9, September 2025.This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan +5 more
wiley +1 more source
Exposing the crumbling justification for absolute prosecutorial discretion in youth filing decisions
Family Court Review, Volume 63, Issue 3, Page 401-414, July 2025.Abstract Can absolute prosecutorial discretion in youth charging decisions—like that allowed under Title 16 in the District of Columbia—continue to withstand legal, scientific, and policy‐based scrutiny? The recently‐approved Restatement of Children and the Law adds to the weight of authorities casting further doubt on the wisdom of such discretion ...
Nina A. Herth, Chinh Q. Le
wiley +1 more source
Oncology Report, 2017 MicroRNAs (miRNAs) are a group of critical players in gastric cancer (GC). Among numerous cancer-related miRNAs, the expression level and functional role of miR-345 in GC has not been investigated.
Aiwen Feng, Xiaoming Yuan, Xiangwei Li
semanticscholar +1 more source
Gene therapy for genetic diseases: challenges and future directions
MedComm, Volume 6, Issue 2, February 2025.The graphical abstract provides an overview of gene therapy approaches, detailing the components of the therapy and the various delivery routes. Both in vivo and ex vivo strategies facilitate the implementation of gene replacement, gene suppression, gene supplementation, and gene editing.
Beibei Qie +4 more
wiley +1 more source