Results 101 to 110 of about 94,100 (113)

Genetic therapies for neurological diseases. [PDF]

Pharmacol Rev
Rahim AA, Kurian MA, Zhou H, Ferguson R, Tabrizi SJ, Lignani G, Aquilina K, Waddington SN.   +7 more
europepmc   +1 more source

Myeloid cells in chronic liver inflammation. [PDF]

Cell Mol Immunol
Patseas D, El-Masry A, Liu Z, Ramachandran P, Triantafyllou E.   +4 more
europepmc   +1 more source

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Sphingomyelin-based PEGylation Cu(DDC)2 Liposomes Prepared via the Dual Function of Cu2+ for Cancer Therapy: Facilitating DDC Loading and Exerting Synergistic Antitumor Effects.

International journal of pharmaceutics, 2022
The old alcohol-aversion drug disulfiram (DSF) has aroused wide attention as a drug repurposing strategy in terms of cancer therapy because of the high antitumor efficacy in combination with copper ion.
Hao Liu, Yihan Kong, Zixu Liu, Xueting Guo, Binghua Yang, Tian Yin, Haibing He, Jingxin Gou, Yu Zhang, Xing Tang   +9 more
semanticscholar   +1 more source

Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC‐induced cholestatic injury by promoting a pro‐restorative inflammatory response

Journal of Pathology, 2022
Despite the well‐known hepatoprotective role of the epidermal growth factor receptor (EGFR) pathway upon acute damage, its specific actions during chronic liver disease, particularly cholestatic injury, remain ambiguous and unresolved.
Nerea Lazcanoiturburu, Juan García-Sáez, Carlos González-Corralejo, C. Roncero, Julián Sanz, Carlos Martín‐Rodríguez, M. P. Valdecantos, A. Martínez‐Palacián, L. Almalé, P. Bragado, Silvia Calero-Pérez, Almudena Fernández, M. García-Bravo, C. Guerra, L. Montoliu, J. Segovia, Á. M. Valverde, I. Fabregat, B. Herrera, Aránzazu Sánchez   +19 more
semanticscholar   +1 more source

Geniposide suppresses liver injury in a mouse model of DDC‐induced sclerosing cholangitis

Phytotherapy Research, 2021
Sclerosing cholangitis, characterized by biliary inflammation, fibrosis, and stricturing, remains one of the most challenging conditions of clinical hepatology. Geniposide (GE) has anti‐inflammatory, hepatoprotective, and cholagogic effects.
Min Wen, Yubei Liu, Ruiying Chen, P. He, Feihua Wu, Rui Li, Yining Lin   +6 more
semanticscholar   +1 more source

DDC: Dynamic duty cycle for improving delay and energy efficiency in wireless sensor networks

Journal of Network and Computer Applications, 2019
Due to the limit of computation and storage capability of devices, traditional security techniques face many challenges in the process of data transmission.
Yuxin Liu, Anfeng Liu, Ning Zhang, Xiao Liu, Mingchi Ma, Yanling Hu   +5 more
semanticscholar   +1 more source

Paclitaxel alleviates the sepsis-induced acute kidney injury via lnc-MALAT1/miR-370-3p/HMGB1 axis.

Life Science, 2020
AIMS To investigate the effects of paclitaxel on lipopolysaccharide (LPS)-induced acute kidney injury (AKI) and its related mechanisms. MAIN METHODS The sepsis-associated AKI was induced by LPS using HK-2 cells.
Lina Xu, G. Hu, P. Xing, Min-Jie Zhou, Donglian Wang   +4 more
semanticscholar   +1 more source

Protective effect of herbal medicine Huangqi decoction against chronic cholestatic liver injury by inhibiting bile acid-stimulated inflammation in DDC-induced mice.

Phytomedicine, 2019
BACKGROUND Huangqi decoction (HQD), a classic traditional herbal medicine, has been used for liver fibrosis, but its effect on intrahepatic chronic cholestatic liver injury remains unknown.
Wenkai Li, Guofeng Wang, Tianming Wang, Yuan-yuan Li, Yi-fei Li, Xin Lu, Yahang Wang, Hua Zhang, Ping Liu, Jiasheng Wu, Yueming Ma   +10 more
semanticscholar   +1 more source

Next-generation sequencing reveals alternative L-DOPA decarboxylase (DDC) splice variants bearing novel exons, in human hepatocellular and lung cancer cells.

Gene, 2020
The human L-DOPA decarboxylase (DDC) is an enzyme that displays a pivotal role in metabolic processes. It is implicated in various human disorders, including hepatocellular and lung cancer.
Maria Papatsirou, P. Adamopoulos, P. Artemaki, Vasiliki P Georganti, A. Scorilas, D. Vassilacopoulou, C. Kontos   +6 more
semanticscholar   +1 more source

DDC-Outlier: Preventing Medication Errors Using Unsupervised Learning

IEEE journal of biomedical and health informatics, 2019
Electronic health records have brought valuable improvements to hospital practices by integrating patient information. In fact, the understanding of these data can prevent mistakes that may put patients’ lives at risk.
H. D. P. D. Santos, A. Ulbrich, Vinicius Woloszyn, Renata Vieira   +3 more
semanticscholar   +1 more source