Results 1 to 10 of about 42,878 (98)

USP38, FREM3, SDC1, DDC, and LOC727982 Gene Polymorphisms and Differential Susceptibility to Severe Malaria in Tanzania. [PDF]

J Infect Dis, 2015
Populations exposed to Plasmodium falciparum infection develop genetic mechanisms of protection against severe malarial disease. Despite decades of genetic epidemiological research, the sickle cell trait (HbAS) sickle cell polymorphism, ABO blood group ...
Manjurano A, Sepúlveda N, Nadjm B, Mtove G, Wangai H, Maxwell C, Olomi R, Reyburn H, Drakeley CJ, Riley EM, Clark TG, in Collaboration With MalariaGEN.   +11 more
europepmc   +2 more sources

Melanin Synthesis Pathway Interruption: CRISPR/Cas9-mediated Knockout of dopa decarboxylase (DDC) in Harmonia axyridis (Coleoptera: Coccinellidae)

Journal of Insect Science, 2022
CRISPR/Cas9 technology is a very powerful genome editing tool and has been used in many insect species for functional genomics studies through targeted gene mutagenesis.
Meng-meng Wu, Xu Chen, Qingbiao Xu, L. Zang, Su Wang, Ming Li, D. Xiao   +6 more
semanticscholar   +1 more source

Short term associations of ambient nitrogen dioxide with daily total, cardiovascular, and respiratory mortality: multilocation analysis in 398 cities

British medical journal, 2021
Objective To evaluate the short term associations between nitrogen dioxide (NO2) and total, cardiovascular, and respiratory mortality across multiple countries/regions worldwide, using a uniform analytical protocol. Design Two stage, time series approach,
Xia Meng, Cong Liu, Renjie Chen, F. Sera, A. Vicedo-Cabrera, Ai Milojevic, Yuming Guo, S. Tong, M. Coelho, P. Saldiva, É. Lavigne, P. M. Correa, N. V. Ortega, S. Osorio, García, J. Kyselý, A. Urban, H. Orru, M. Maasikmets, J. Jaakkola, N. Ryti, V. Huber, A. Schneider, K. Katsouyanni, A. Analitis, M. Hashizume, Y. Honda, Chris Fook Sheng Ng, B. Nunes, J. Teixeira, I. Holobâcă, S. Fratianni, Ho Kim, A. Tobías, C. Íñiguez, B. Forsberg, Christofer Åström, Martina S. Ragettli, Y. Guo, Shih-chun Pan, Shanshan Li, M. Bell, A. Zanobetti, J. Schwartz, Tangchun Wu, A. Gasparrini, H. Kan   +46 more
semanticscholar   +1 more source

In Arabidopsis thaliana Cd differentially impacts on hormone genetic pathways in the methylation defective ddc mutant compared to wild type

Scientific Reports, 2021
DNA methylation plays an important role in modulating plant growth plasticity in response to stress, but mechanisms involved in such control need further investigation.
M. Pacenza, A. Muto, A. Chiappetta, L. Mariotti, E. Talarico, P. Picciarelli, E. Picardi, L. Bruno, M. B. Bitonti   +8 more
semanticscholar   +1 more source

Preclinical In Vitro Studies with 3D Spheroids to Evaluate Cu(DDC)2 Containing Liposomes for the Treatment of Neuroblastoma

Pharmaceutics, 2021
Preclinical in vitro studies of drug candidates for anticancer therapy are generally conducted on well-established 2D cell models. Unfortunately, these models are unable to mimic the properties of in vivo tumors.
F. Hartwig, Monika Köll-Weber, R. Süss
semanticscholar   +1 more source

Blastic plasmacytoid dendritic cell neoplasms: results of an international survey on 398 adult patients.

Blood Advances, 2020
The purpose of this study is to describe the clinical and prognostic features and to evaluate the outcome of different therapeutic approaches among patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) who have been diagnosed and treated in ...
K. Laribi, Alix Baugier de Materre, M. Sobh, L. Cerroni, C. Valentini, T. Aoki, R. Suzuki, K. Takeuchi, A. Frankel, C. Cota, D. Ghez, R. Le Calloch, L. Pagano, T. Petrella   +13 more
semanticscholar   +1 more source

Trends in domiciliary dental care including the need for oral appliances and dental technicians in Japan.

Journal of Oral Science, 2018
The need for domiciliary dental care (DDC) for people requiring long-term nursing care is increasing as the super-aged society of Japan grows still older.
S. Kamijo, Kumiko Sugimoto, M. Oki, Yumi Tsuchida, Tetsuya Suzuki   +4 more
semanticscholar   +1 more source

Determination of consensus kQ values for megavoltage photon beams for the update of IAEA TRS-398

Physics in Medicine and Biology, 2020
The IAEA is currently coordinating a multi-year project to update the TRS-398 Code of Practice for the dosimetry of external beam radiotherapy based on standards of absorbed dose to water.
P. Andreo, D. Burns, R. Kapsch, M. McEwen, S. Vatnitsky, C. Andersen, F. Ballester, J. Borbinha, F. Delaunay, P. Francescon, M. Hanlon, L. Mirzakhanian, B. Muir, J. Ojala, C. Oliver, M. Pimpinella, M. Pinto, L. D. de Prez, J. Seuntjens, L. Sommier, P. Teles, J. Tikkanen, J. Vijande, K. Zink   +23 more
semanticscholar   +1 more source

Revised Exon Structure of l-DOPA Decarboxylase (DDC) Reveals Novel Splice Variants Associated with Colorectal Cancer Progression

International Journal of Molecular Sciences, 2020
Colorectal cancer (CRC) is a highly heterogenous malignancy with an increased mortality rate. Aberrant splicing is a typical characteristic of CRC, and several studies support the prognostic value of particular transcripts in this malignancy.
P. Artemaki, Maria Papatsirou, Michaela A. Boti, P. Adamopoulos, S. Christodoulou, D. Vassilacopoulou, A. Scorilas, C. Kontos   +7 more
semanticscholar   +1 more source

L-Dopa-Decarboxylase (DDC) Is a Positive Prognosticator for Breast Cancer Patients and Epinephrine Regulates Breast Cancer Cell (MCF7 and T47D) Growth In Vitro According to Their Different Expression of Gi- Protein- Coupled Receptors

International Journal of Molecular Sciences, 2020
A coherence between thyroid dysfunction and breast cancer incidence exists. Thyroid hormone metabolites bind to TAAR1 (trace amine-associated receptor 1) and through that modulate the serotonergic and dopaminergic system.
E. Tremmel, C. Kuhn, T. Kaltofen, T. Vilsmaier, D. Mayr, S. Mahner, N. Ditsch, U. Jeschke, A. Vattai   +8 more
semanticscholar   +1 more source