Results 11 to 20 of about 3,084 (68)
Brain Specific RagA Overexpression Triggers Depressive‐Like Behaviors in Mice via Activating ADORA2A Signaling Pathway [PDF]
Advanced Science, Volume 11, Issue 45, December 4, 2024.The overexpression of brain‐specific RagA leads to depressive‐like behaviors, memory impairment, and hippocampal neuron loss in mice. This is accompanied by an upregulation of the adenosine A2a receptor (ADORA2A) and coordinated changes in the levels of depression‐related metabolites, proteins, and lncRNA.
Jia Zhao +3 more
wiley +2 more sources
Properties of diffuse and volume discharges that are important for their applications
High Voltage, Volume 10, Issue 1, Page 126-136, February 2025.Abstract Diffuse and volume discharges are currently used widely in various fields. This work compares the properties of diffuse and volume discharges, as well as considers the conditions for their formation at high pressures. The main attention is paid to a diffuse discharge (DD). It has been shown that the ignition of a diffuse discharges is preceded
Victor Tarasenko +5 more
wiley +1 more source
Journal of Anatomy, Volume 246, Issue 2, Page 299-315, February 2025.Bite force in parrots has been explored using data from muscle masses. The values were validated by comparison with data for bite force collected from live parrots. The parrot's reputation for a strong bite force is well founded. Abstract Jaw morphology and function determine the range of dietary items that an organism can consume.
Shannon L. Harrison +3 more
wiley +1 more source
Guidelines for preparation and flow cytometry analysis of human nonlymphoid tissue DC
European Journal of Immunology, Volume 55, Issue 1, January 2025.We here provide detailed protocols for isolating single cell suspension from human nonlymphoid tissues, such as gingiva, lung, intestine, skin, and different tumor tissues as well as tumor‐draining lymph nodes. Further, we provide gating strategies for flow cytometric analysis of human DC subpopulations in diverse nonlymphoid tissues.
Diana Dudziak +29 more
wiley +1 more source
A comprehensive survey of crowd density estimation and counting
IET Image Processing, Volume 19, Issue 1, January/December 2025.This paper provides a comprehensive survey of crowd density estimation and counting approaches, categorizing them into traditional and deep learning‐based approaches. It focuses on analysing deep learning‐based methods, discusses training and evaluation details, and compares the performance of classical models. The paper also discusses future prospects,
Mingtao Wang, Xin Zhou, Yuanyuan Chen
wiley +1 more source
Tungsten's Role in Enhancing Sintering Resistance of Fe‐W Hierarchical Foams during Redox Cycling
Advanced Functional Materials, Volume 34, Issue 52, December 23, 2024.Increasing W concentration to 18–25 at.% in lamellar Fe‐W foams introduces a sufficient volume fraction of W‐rich phases (λ‐Fe2W and FeWO4 in the reduced and oxidized states respectively) to inhibit the sintering of lamellae with hierarchical porosity during high‐temperature redox cycling.
Ming Chen +2 more
wiley +1 more source
The recent development, application, and future prospects of muscle atrophy animal models
MedComm – Future Medicine, Volume 3, Issue 4, December 2024.Understanding muscle atrophy: causes and models This review explores various experimental mouse models used to simulate muscle atrophy, caused by factors such as aging, chronic diseases, malnutrition, and reduced physical activity. The review emphasizes the development and limitations of these models to better understand and address the multifaceted ...
Gongchang Zhang +8 more
wiley +1 more source
Liquid Crystalline Hydroxyapatite Nanorods Orchestrate Hierarchical Bone‐Like Mineralization
Small, Volume 20, Issue 52, December 27, 2024.Unidirectional liquid crystalline hydroxyapatite nanorods guide the growth and osteogenesis of stem cells and the formation of ordered extracellular matrix and calcium deposits at multi‐scales. The PI3k‐Akt signaling pathway mediated by two key genes COL1A1 and COL4A6 is activated in this process.
Jishizhan Chen +3 more
wiley +1 more source
European Journal of Neurology, Volume 31, Issue 12, December 2024.Abstract Background and Purpose Multiple system atrophy (MSA) is a progressive, adult‐onset neurodegenerative disorder clinically characterized by combinations of autonomic failure, parkinsonism, cerebellar ataxia and pyramidal signs. Although a few genetic factors have been reported to contribute to the disease, its mutational profiles have not been ...
Xu‐Ying Li +9 more
wiley +1 more source
Metabolic and multi-model intravoxel incoherent motion parameters based 18F-FDG PET/MRI for predicting subtypes of inoperable non-small cell lung cancer. [PDF]
BMC CancerHuang Z +10 more
europepmc +1 more source