Results 11 to 20 of about 3,589 (66)

Virus-Mediated Self-Assembly of Functional Cyclodextrins for Antiviral Inhibition. [PDF]

Angew Chem Int Ed Engl
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Hernando PJ, Boulo L, Lavnevich L, Teyssou E, Marot S, Gothland A, Guigner JM, Marcelin AG, Ménand M, Calvez V, Sollogoub M.   +10 more
europepmc   +3 more sources

Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero, Line Mørkholt Lund, Lasse Hyldgaard Klausen, Obinna Markraphael Ajunwa, Mingdong Dong, Rikke Louise Meyer, Victoria Birkedal, Kai Thormann   +7 more
wiley   +2 more sources

Models of DG‐Carbon Bands in Raman Spectra: Effects of Basis Functions and Initial Values on the Uniqueness and S/N of Fits Obtained for Atmospheric Aerosol Using Automated Methods

Journal of Raman Spectroscopy, EarlyView.
Raman spectra containing D/G features are fit using combinations of basis functions and initial conditions. Fits with two Lorentzian functions converged to a single optimized fit even with variation of initial peak positions. For five‐band fits, sometimes the final fit varied with initial conditions, and constraints on peak center position were ...
David C. Doughty, Steven C. Hill
wiley   +1 more source

Multiscale numerical sensitivity simulations of a mesoscale gravity‐wave event

Quarterly Journal of the Royal Meteorological Society, EarlyView.
High‐resolution WRF simulations of the February 14–15, 1992 STORM‐FEST event show that mesoscale gravity‐wave genesis occurs via geostrophic adjustment within an upper‐level unbalanced jet, while wave ducting governs maintenance. High‐resolution (1 km), improved physical parameterization, and targeted sensitivity simulations demonstrate that upstream ...
Rajan Bhandari, Michael L. Kaplan, Ananya Sen   +2 more
wiley   +1 more source

Sanctions, National Security, and Free Speech

Global Policy, EarlyView.
ABSTRACT A fundamental, but largely overlooked, aspect of the New Washington Consensus is the use of national security arguments to restrict speech and punish disfavored speakers. Although the United States has a longer history of using sanctions to restrict speech in the terrorism context, it has recently applied sanctions to restrict political speech,
Joshua Andresen
wiley   +1 more source

Transcriptomic profiling of subpopulations of mouse embryonic subplate neurons

Journal of Anatomy, EarlyView.
To study gene expression in subpopulations of cortical subplate neurons (Lpar1‐EGFP‐positive and D1B‐positive SpN clusters), we applied gene expression profiling, including bulk microarray analysis, single‐cell RNA sequencing (scRNA‐seq), and Visium spatial transcriptomics, and identified both overlapping and unique gene expression signatures ...
Hitomi Achiwa, Yuichiro Hara, Hideya Kawaji, Minori Oshima, Noe Kaneko, Ayumu Morioka, Anna Hoerder‐Suabedissen, Zoltán Molnár, Chiaki Ohtaka‐Maruyama   +8 more
wiley   +1 more source

Anaplastic cutaneous plasmacytoma in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Extramedullary cutaneous plasmacytoma is an uncommon tumour in dogs and rare in cats, often linked to chronic inflammation or prolonged antigenic stimulation. It typically affects middle‐aged to older dogs, involving the head, trunk, limbs and digits.
André Castilhano Marcelino Silva, Júlia Kaori Hayashi, Danielle Cavalcanti Carvalho de Diniz, Maria Lucia Gomes Lourenço, Luiz Henrique Araujo de Machado   +4 more
wiley   +1 more source

ApoE lipidation state directs immunometabolic reprogramming of human microglia

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION ApoE ε4 is the strongest genetic risk factor for Alzheimer's disease (AD). Emerging evidence suggests that ApoE4 increases AD risk by disrupting microglial metabolism and function. However, whether ApoE lipidation state contributes to microglial dysfunction remains poorly understood. METHODS Human microglia were treated with lipid‐
Tsion G. Shiferaw, Snigdha Sarkar, Katelyn M. Baker, Rowan S. Wooldridge, Hannah M. Binfet, Victoria N. Prozapas, Chinemerem P. Ogbu, Athena A. Schepmoes, Isaac K. Attah, Christy S. Niemeyer, Kayla G. Sprenger, James E. Hassell, Robert H. Eckel, John T. Melchior, Kimberley D. Bruce   +14 more
wiley   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, Volume 41, Issue 10, Page 1105-1118, October 2026.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Psychological impacts of APOE genotype disclosure among Latinos in New York City: a randomized controlled trial

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Latinos face increased Alzheimer's disease (AD) risk but are underrepresented in studies of APOE genotype disclosure. We evaluated the psychological impacts of APOE disclosure in the Información de la Enfermedad de Alzheimer para Latinos (IDEAL) study, a randomized controlled trial among Latinos in New York City.
Ruth Ottman, John B. Wetmore, Cheng‐Shiun Leu, Wendy R. Uhlmann, Jill Goldman, Sophia Rodriguez, Daniela Diaz Caro, María Cabán, Sarah McCain, Drew Blasco, Rafael A. Lantigua, Ana Abraido‐Lanza, Wendy K. Chung, J. Scott Roberts, Karolynn Siegel   +14 more
wiley   +1 more source