Results 61 to 70 of about 726,513 (83)

Effects of drugs modifying catecholamine synthesis on plasma LH and ovulation in the rat.

Neuroendocrinology, 1974
Relatively large doses of alpha methyl paratyrosine (α-MPT) (400 mg/kg, i.p.) to inhibit catecholamine synthesis were capable of blocking both the pre-ovulatory elevation in plasma LH and ovulation in proestrous rats.
S. Kalra, S. Mccann
semanticscholar   +1 more source

Diethyldithiocarbamate Causes Nigral Cell Loss and Dopamine Depletion with Nontoxic Doses of MPTP

Experimental Neurology, 1999
Although nontoxic when administered alone, diethyldithiocarbamate (DDC) is known to enhance the dopamine-depleting effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse striatum.
Tessa L. Walters, I. Irwin, K. Delfani, J. Langston, A. Janson   +4 more
semanticscholar   +1 more source

Diethyldithiocarbamate Potentiates the Neurotoxicity of In Vivo l‐Methyl‐4‐Phenyl‐1, 2, 3, 6‐Tetrahydropyridine and of In Vitro 1‐Methyl‐4‐Phenylpyridinium

Journal of Neurochemistry, 1991
Diethyldithiocarbamic acid (DDC) potentiates in vivo neurotoxicity of 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine (MPTP) and in vitro neurotoxicity of 1‐methyl‐4‐phenylpyridinium (MPP+). Male C57B1/6 mice were given two or five injections of MPTP (30
D. Miller, J. Reinhard, A. Daniels, J. O'Callaghan   +3 more
semanticscholar   +1 more source

Managing treatment fluctuations in Parkinson disease

Neurology, 2019
The first truly effective medical therapy for Parkinson disease (PD), levodopa, was introduced in the 1960s. Patients had to take huge doses of levodopa, with treatment limited by peripheral decarboxylation of levodopa to dopamine by dopa decarboxylase ...
W. Metzer, F. B. Rodrigues
semanticscholar   +1 more source

ATBF1‐A protein, but not ATBF1‐B, is preferentially expressed in developing rat brain

The Journal of comparative neurology, 2003
The ATBF1 gene encodes transcription factors containing four homeodomains and multiple zinc finger motifs. However, the gene products have yet to be identified and the role remains unknown in vivo.
Y. Ishii, M. Kawaguchi, K. Takagawa, T. Oya, S. Nogami, A. Tamura, Y. Miura, A. Ido, N. Sakata, T. Hashimoto‐Tamaoki, Tomoatsu Kimura, Takayoshi Saito, T. Tamaoki, M. Sasahara   +13 more
semanticscholar   +1 more source

A fractional sample rate conversion filter for a software radio receiver on FPGA

IEEE Region 10 Conference, 2014
Sample rate conversion for a software radio receiver is one of the critical tasks. Due to the phenomenon of bandpass sampling, digitization of a very high intermediate frequency incorporating different wireless communication standards has to undergo ...
Ashok Agarwal, Lakshmi Boppana, R. Kodali   +2 more
semanticscholar   +1 more source

The protective effects of ascorbic acid, cimetidine, and nifidipine on diethyldithiocarbamate-induced hepatic toxicity in albino rats

Drug and chemical toxicology (New York, N.Y. 1978), 2011
The aim of the present work was to clarify the involvement of free radicals, cytochrome P450 toxic metabolites, and deregulation of calcium homeostasis in the mechanism of diethyldithiocarbamate (DDC) hepatotoxicity.
Khadiga Mohammed Gaafa, Mohammed Badawy, A. Hamza   +2 more
semanticscholar   +1 more source

Inhibition of the alpha-amidation of gastrin: effects on gastric acid secretion.

American Journal of Physiology, 1990
Formation of biologically active amidated gastrin from glycine-extended progastrin processing intermediates (G-Gly) is achieved via the action of peptidyl-glycyl alpha-amidating monooxygenase.
C. Dickinson, L. Marino, T. Yamada
semanticscholar   +1 more source

Inter-Journal Knowledge Map using Citation Information and Subject Classification

, 2013
In this paper, citation data that is cross?referenced among journals is established using reference data in CrossRef. Using the established citation data, cited information is created and using DDC classification information, journals are classified ...
Seok-Hyoung Lee, Seo-Young Jeong, Kwang-Young Kim   +2 more
semanticscholar   +1 more source

Developmental toxicity of orally administered 2',3'-dideoxycytidine in mice.

Teratology, 1990
2',3'-Dideoxycytidine (DDC), a potent inhibitor of human immunodeficiency virus (HIV), is presently undergoing clinical trials as a promising anti-AIDS drug.
P. Lindström, M. Harris, A. Hoberman, J. Dunnick, R. Morrissey   +4 more
semanticscholar   +1 more source