Results 1 to 10 of about 534 (68)

Different ethanol exposure durations affect cytochrome P450 2E1-mediated sevoflurane metabolism in rat liver. [PDF]

BMC Anesthesiol
Jiang W, Zhang M, Cao R, Wang X, Zuo Y.
europepmc   +1 more source

<i>Ballota hirsuta</i> Benth Arrests the Cell Cycle, Induces Apoptosis and Inhibits the Invasion of MCF-7 and MDA-MB-231 Cell Lines in 2D and 3D Models. [PDF]

Int J Mol Sci
Martínez-Méndez DDC, Sánchez-Mundo ML, Ortiz-León LA, Álvarez-Salas LM, Rosales-García VH, Rodríguez-Campos J, Jaramillo-Flores ME.   +6 more
europepmc   +1 more source

A Real-World Retrospective Study to Evaluate the Reliability of Cetuximab plus Capecitabine versus Capecitabine as Maintenance Therapy in Patients with RAS and BRAF Wild-Type Metastatic Colorectal Cancer. [PDF]

Med Princ Pract
Li J, Zhang H, Guo X, Dong S, Li Y, Huang W, Yuan X.   +6 more
europepmc   +1 more source

Iridoids in gardenia fruit: key components in liver disease therapy. [PDF]

Front Nutr
Cao Q, Du X, Liu A, Li Q, Luo Q, Chen Y, Wang R, Meng L.   +7 more
europepmc   +1 more source

Mitochondria-targeted nanovesicles for ursodeoxycholic acid delivery to combat neurodegeneration by ameliorating mitochondrial dysfunction. [PDF]

J Nanobiotechnology
Zhang S, Li M, Li Y, Yang S, Wang J, Ren X, Wang X, Bai L, Huang J, Geng Z, Han G, Fang Y, Su J.   +12 more
europepmc   +1 more source

Nonsmall-cell lung cancer treatment: current status of drug repurposing and nanoparticle-based drug delivery systems. [PDF]

Turk J Biol
Inci TG, Acar S, Turgut-Balik D.
europepmc   +1 more source

Protein Tyrosine Phosphatase Receptors N and N2 Control Pituitary Melanotroph Development and POMC Expression.

Endocrinology
Constantin S, Sokanovic SJ, Mochimaru Y, Dams AL, Smiljanic K, Prévide RM, Nessa N, Carmona GN, Stojilkovic SS.   +8 more
europepmc   +1 more source

Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia. [PDF]

Adv Sci (Weinh)
Arf1 defects activate the AKT‐mTORC1‐SREBP1‐FASN pathway to increase lipid synthesis and disrupt ER‐mitochondrial‐lysosomal homeostasis in neurons. Impaired mitochondria secrete damaged mtDNA via mitochondria‐derived extracellular vesicles, which is phagocytosed by the microglia and activated inflammation signaling.
Li X, Jin S, Wang D, Wu Y, Tang X, Liu Y, Yao T, Han S, Sun L, Wang Y, Hou SX.   +10 more
europepmc   +2 more sources

Interleukin‐7 improves the fitness of regulatory T cells for adoptive transfer

Immunology, Volume 170, Issue 4, Page 540-552, December 2023., 2023
Regulatory T cell (Treg) expanded in the presence of interleukin‐7 (IL‐7, IL‐7M) display a CD45RA+CD62L+CD95+ phenotype and are less suppressive that Treg expanded with the standard method (StM). Once infused in vivo IL‐7M‐Treg persist longer and showed similar suppressive activity compared to StM‐Treg.
Ilaria Cosorich, Jessica Filoni, Carla Di Dedda, Arianna Ferrari, Tatiana Jofra, Susanna Cesarano, Chiara Bonini, Lorenzo Piemonti, Paolo Monti   +8 more
wiley   +1 more source