Results 1 to 10 of about 451 (67)
Development of In Vitro Parkinson's Disease Model Mediated by MPP+ and α-Synuclein Using Wharton's Jelly Mesenchymal Stem Cells. [PDF]
CNS Neurosci TherA cost‐effective and rapid in vitro model of Parkinson's disease was created using Wharton's Jelly‐derived mesenchymal stem cells by employing MPP+ iodide or A53T mutated α‐synuclein. ABSTRACT Main Problem The mechanism behind Parkinson's disease (PD) is still unclear, and a cure to stop its progression is yet to be found.
Gamit N +4 more
europepmc +2 more sources
Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]
MedComm (2020)Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Li G +13 more
europepmc +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
MedComm, Volume 6, Issue 9, September 2025.Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen +4 more
wiley +1 more source
“Is Lobbying for Losers?”: Corporate Behavior and Canadian Military Procurement Contracting
Regulation &Governance, Volume 19, Issue 2, Page 558-582, April 2025.ABSTRACT Lobbying is a multi‐faceted phenomenon that involves interest groups and corporations contacting politicians and officials in order to try to achieve their policy preferences. While interest group policy‐related lobbying has received a great deal of attention, studies of corporate contract lobbying are rarer even though this is a much older ...
Andrea Migone +4 more
wiley +1 more source
Advanced Optical Materials, Volume 13, Issue 6, February 24, 2025.Highly circularly polarised luminescence (CPL) is achieved by combining achiral aggregation‐induced emission fluorogens (AIEgens) with chiral, supramolecular nanotubes. This phenomenon is enabled by the hierarchical enhancement of chiroptical properties from single molecules to individual nanotubes and, finally, superstructures formed by nanotubes in ...
Mateusz Pawlak +12 more
wiley +1 more source
Antibacterial performance of Co–Zn ferrite nanoparticles under visible light irradiation
Journal of Chemical Technology &Biotechnology, Volume 100, Issue 2, Page 428-437, February 2025.Abstract BACKGROUND To address water scarcity and promote sustainable resource management, more efficient and cost‐effective water treatment solutions are necessary. Particularly, pathogens in drinking water are a topic of growing concern. One promising technology is the use of photocatalytic nanoparticles activated by visible light as antibacterial ...
Alicia G. Gubieda +7 more
wiley +1 more source
Journal of Anatomy, Volume 246, Issue 2, Page 299-315, February 2025.Bite force in parrots has been explored using data from muscle masses. The values were validated by comparison with data for bite force collected from live parrots. The parrot's reputation for a strong bite force is well founded. Abstract Jaw morphology and function determine the range of dietary items that an organism can consume.
Shannon L. Harrison +3 more
wiley +1 more source
Journal of Food Biochemistry, Volume 2025, Issue 1, 2025.Camellia japonica L. seed oil has been widely studied and utilized for its skincare, antioxidant, and anti‐inflammatory effects. However, the anti‐inflammatory activity of the seed cake—a by‐product obtained after oil extraction from C. japonica L. seeds—has not yet been investigated.
Kyung-Wan Baek +8 more
wiley +1 more source