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Mitochondrial DNA Variation, Antiretroviral Therapy, and Incidence of Diabetes Among Men With and Without HIV. [PDF]

open access: yesOpen Forum Infect Dis
Cronin C   +11 more
europepmc   +1 more source

Evolutionarily conserved transcriptional regulators control monoaminergic neuron development

open access: yes
Lewis C   +10 more
europepmc   +1 more source
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Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC‐induced cholestatic injury by promoting a pro‐restorative inflammatory response

Journal of Pathology, 2022
Despite the well‐known hepatoprotective role of the epidermal growth factor receptor (EGFR) pathway upon acute damage, its specific actions during chronic liver disease, particularly cholestatic injury, remain ambiguous and unresolved.
Nerea Lazcanoiturburu   +19 more
semanticscholar   +1 more source

Sphingomyelin-based PEGylation Cu(DDC)2 Liposomes Prepared via the Dual Function of Cu2+ for Cancer Therapy: Facilitating DDC Loading and Exerting Synergistic Antitumor Effects.

International journal of pharmaceutics, 2022
The old alcohol-aversion drug disulfiram (DSF) has aroused wide attention as a drug repurposing strategy in terms of cancer therapy because of the high antitumor efficacy in combination with copper ion.
Hao Liu   +9 more
semanticscholar   +1 more source

Geniposide suppresses liver injury in a mouse model of DDC‐induced sclerosing cholangitis

Phytotherapy Research, 2021
Sclerosing cholangitis, characterized by biliary inflammation, fibrosis, and stricturing, remains one of the most challenging conditions of clinical hepatology. Geniposide (GE) has anti‐inflammatory, hepatoprotective, and cholagogic effects.
Min Wen   +6 more
semanticscholar   +1 more source

Next-generation sequencing reveals alternative L-DOPA decarboxylase (DDC) splice variants bearing novel exons, in human hepatocellular and lung cancer cells.

Gene, 2020
The human L-DOPA decarboxylase (DDC) is an enzyme that displays a pivotal role in metabolic processes. It is implicated in various human disorders, including hepatocellular and lung cancer.
Maria Papatsirou   +6 more
semanticscholar   +1 more source

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