Results 11 to 20 of about 54,918 (114)

CircRAB3IP upregulates twist family BHLH transcription factor (TWIST1) to promote osteosarcoma progression by sponging miR-580-3p

Bioengineered, 2021
Circular RNAs (circ RNAs) have been found to play an important role in cancer development. However, the role of circRAB3IP in osteosarcoma (OS) is unclear.
Guojun Tang, Linghua Liu, Zhihong Xiao, Shuo Wen, Liangyuan Chen, Peng Yang   +5 more
semanticscholar   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

British Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jurg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +28 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Transporters

British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +27 more
wiley   +1 more source

Commodity risk assessment of Prunus persica and P. dulcis plants from Türkiye

EFSA Journal, Volume 21, Issue 1, January 2023., 2023
Abstract The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’. This Scientific Opinion covers plant health risks posed by plants of Prunus persica and P.
EFSA Panel on Plant Health (PLH), Claude Bragard, Paula Baptista, Elisavet Chatzivassiliou, Paolo Gonthier, Josep Anton Jaques Miret, Annemarie Fejer Justesen, Alan MacLeod, Christer Sven Magnusson, Panagiotis Milonas, Juan A Navas‐Cortes, Stephen Parnell, Roel Potting, Philippe Lucien Reignault, Emilio Stefani, Hans‐Hermann Thulke, Wopke Van der Werf, Antonio Vicent Civera, Lucia Zappalà, Andrea Lucchi, Pedro Gómez, Gregor Urek, Umberto Bernardo, Giovanni Bubici, Anna Vittoria Carluccio, Michela Chiumenti, Francesco Di Serio, Elena Fanelli, Agata Kaczmarek, Cristina Marzachì, Olaf Mosbach‐Schulz, Jonathan Yuen   +31 more
wiley   +1 more source

Incidence of hypertension in people with HIV who are treated with integrase inhibitors versus other antiretroviral regimens in the RESPOND cohort consortium

HIV Medicine, Volume 23, Issue 8, Page 895-910, September 2022., 2022
Abstract Objective To compare the incidence of hypertension in people living with HIV receiving integrase strand transfer inhibitor (INSTI)‐based antiretroviral therapy (ART) versus non‐nucleoside reverse transcriptase inhibitors (NNRTIs) or boosted protease inhibitors (PIs) in the RESPOND consortium of HIV cohorts.
Dathan M. Byonanebye, Mark N. Polizzotto, Bastian Neesgaard, Mario Sarcletti, Raimonda Matulionyte, Dominique L. Braun, Antonella Castagna, Stéphane de Wit, Ferdinand Wit, Eric Fontas, Jörg Janne Vehreschild, Jan Vesterbacka, Lauren Greenberg, Camilla Hatleberg, Harmony Garges, Joel Gallant, Alain Volny Anne, Angela Öllinger, Iwona Mozer‐Lisewska, Bernard Surial, Vincenzo Spagnuolo, Coca Necsoi, Marc van der Valk, Amanda Mocroft, Matthew Law, Lene Ryom, Kathy Petoumenos, the RESPOND study group, M Hillebregt, N Rose, J Hutchinson, R Zangerle, H Appoyer, M Delforge, C Stephan, M Bucht, N Chkhartishvili, O Chokoshvili, C Mussini, V Borghi, C Pradier, K Dollet, C Caissotti, J Casabona, JM Miro, C Smith, F Lampe, M Johnson, F Burns, C Chaloner, A Lazzarin, A Poli, A Sönnerborg, K Falconer, V Svedhem, H Günthard, B Ledergerber, H Bucher, A Scherrer, JC Wasmuth, J Rockstroh, G Fätkenheuer, M Stecher, N Schulze, B Franke, Lene Ryom, J Rooney, I McNicholl, V Vannappagari, G Wandeler, J Lundgren, J Kowalska, D Raben, A Mocroft, L Peters, ED Williams, C Necsoi, A D’Arminio Monforte, A Bruguera, Nikos Dedes, Luis Mendao, JF Larsen, N Jaschinski, ML Jakobsen, T Bruun, A Bojesen, EV Hansen, AK Traytel, TW Elsing, D Kristensen, T Weide, L Bansi‐Matharu, A Pelchen‐Matthews   +92 more
wiley   +1 more source

The Limited Palette for Photonic Block‐Copolymer Materials: A Historical Problem or a Practical Limitation?

Angewandte Chemie, Volume 134, Issue 22, May 23, 2022., 2022
The self‐assembly of block‐copolymers into photonic films and pigments has drawn significant attention due to the tunability of the optical response. In this Scientific Perspective we identify and rationalize the limited range of monomers and polymerization methods employed to produce such structurally colored materials to date.
Zhen Wang, Chun Lam Clement Chan, Richard M. Parker, Silvia Vignolini   +3 more
wiley   +1 more source

Revised Exon Structure of l-DOPA Decarboxylase (DDC) Reveals Novel Splice Variants Associated with Colorectal Cancer Progression

International Journal of Molecular Sciences, 2020
Colorectal cancer (CRC) is a highly heterogenous malignancy with an increased mortality rate. Aberrant splicing is a typical characteristic of CRC, and several studies support the prognostic value of particular transcripts in this malignancy.
P. Artemaki, Maria Papatsirou, Michaela A. Boti, P. Adamopoulos, S. Christodoulou, D. Vassilacopoulou, A. Scorilas, C. Kontos   +7 more
semanticscholar   +1 more source

L-Dopa-Decarboxylase (DDC) Is a Positive Prognosticator for Breast Cancer Patients and Epinephrine Regulates Breast Cancer Cell (MCF7 and T47D) Growth In Vitro According to Their Different Expression of Gi- Protein- Coupled Receptors

International Journal of Molecular Sciences, 2020
A coherence between thyroid dysfunction and breast cancer incidence exists. Thyroid hormone metabolites bind to TAAR1 (trace amine-associated receptor 1) and through that modulate the serotonergic and dopaminergic system.
E. Tremmel, C. Kuhn, T. Kaltofen, T. Vilsmaier, D. Mayr, S. Mahner, N. Ditsch, U. Jeschke, A. Vattai   +8 more
semanticscholar   +1 more source

A LHFPL3-AS1/miR-580-3p/STAT3 Feedback Loop Promotes the Malignancy in Melanoma via Activation of JAK2/STAT3 Signaling

Molecular Cancer Research, 2020
Melanoma is one of the severe skin cancers, accounting for three fourths of all deaths caused by skin cancers and gathering attention from researchers.
Qian Peng, Linbo Liu, H. Pei, Jianwen Zhang, Minjing Chen, Xiaomei Zhai   +5 more
semanticscholar   +1 more source

Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease

Acta Neuropathologica
Parkinson’s disease (PD) starts at the molecular and cellular level long before motor symptoms appear, yet there are no early-stage molecular biomarkers for diagnosis, prognosis prediction, or monitoring therapeutic response.
J. Rutledge, B. Lehallier, Pardis Zarifkar, P. M. Losada, M. Shahid-Besanti, D. Western, P. Gorijala, S. Ryman, M. Yutsis, Gayle K. Deutsch, Elizabeth C. Mormino, A. Trelle, Anthony D. Wagner, G. Kerchner, Lu Tian, C. Cruchaga, Victor W. Henderson, T. Montine, P. Borghammer, Tony Wyss-Coray, K. Poston   +20 more
semanticscholar   +1 more source