Results 31 to 40 of about 38,884 (111)

Deep Learning‐Enhanced Chemiluminescence Vertical Flow Assay for High‐Sensitivity Cardiac Troponin I Testing

Small, Volume 21, Issue 11, March 19, 2025.
This study presents a chemiluminescence vertical flow assay (CL‐VFA) for high‐sensitivity detection of cardiac troponin I (cTnI), a critical biomarker for assessing myocardial infarction. By integrating innovations in CL‐based sensing, portable reader‐based imaging, and deep learning analysis, the CL‐VFA achieves rapid, cost‐effective, and precise ...
Gyeo‐Re Han, Artem Goncharov, Merve Eryilmaz, Shun Ye, Hyou‐Arm Joung, Rajesh Ghosh, Emily Ngo, Aoi Tomoeda, Yena Lee, Kevin Ngo, Elizabeth Melton, Omai B. Garner, Dino Di Carlo, Aydogan Ozcan   +13 more
wiley   +1 more source

LncRNA NEAT1 promotes apoptosis and inflammation in LPS-induced sepsis models by targeting miR-590-3p

Experimental and Therapeutic Medicine, 2020
Sepsis is a complication of infection caused by disease or trauma. Increasing evidence have shown that long noncoding RNAs (lncRNAs) are involved in the regulation of sepsis. However, the mechanism of lncRNA nuclear enriched abundant transcript 1 (NEAT1)
Lingling Liu, Fengtao Liu, Zhilu Sun, Zheng-Liang Peng, Ting You, Ziying Yu   +5 more
semanticscholar   +1 more source

Economic Viability of Scaling Improved Bean Technologies in Burundi and Zimbabwe

Food and Energy Security, Volume 14, Issue 1, January/February 2025.
ABSTRACT Scaling improved bean varieties and complementary technologies are important to improve crop productivity incomes and food and nutrition security in Sub‐Saharan Africa. In Burundi and Zimbabwe, bean technologies were promoted through a demand‐led and public–private partnership model.
Ochieng Justus, Joel Maina, Doug White, Jean Claude Rubyogo, Eric Nduwarugira, Eliud Birachi, Ruth Chepchirchir, Enid Katungi, Eileen Nchanji, Sylvia Kalemera, Mercy Mutua, Andrew Chiwawa, Blaise Ndabashinze, Bararyenya Astère, Nepomuscene Ntukamazina, Shylet Tsekenedza   +15 more
wiley   +1 more source

Revised Exon Structure of l-DOPA Decarboxylase (DDC) Reveals Novel Splice Variants Associated with Colorectal Cancer Progression

International Journal of Molecular Sciences, 2020
Colorectal cancer (CRC) is a highly heterogenous malignancy with an increased mortality rate. Aberrant splicing is a typical characteristic of CRC, and several studies support the prognostic value of particular transcripts in this malignancy.
P. Artemaki, Maria Papatsirou, Michaela A. Boti, P. Adamopoulos, S. Christodoulou, D. Vassilacopoulou, A. Scorilas, C. Kontos   +7 more
semanticscholar   +1 more source

miR-590-3p Alleviates diabetic peripheral neuropathic pain by targeting RAP1A and suppressing infiltration by the T cells.

Acta Biochimica Polonica, 2020
BACKGROUND MicroRNAs play a crucial role in diabetic peripheral neuropathic pain (DPNP). miR-590-3p is a novel miRNA and involved in multiple diseases. However, the pathological mechanism of miR-590-3p in DPNP needs to be elucidated.
Yihua Wu, Ye-Song Gu, B. Shi
semanticscholar   +1 more source

Dynamic Field Theory of Executive Function: Identifying Early Neurocognitive Markers

Monographs of the Society for Research in Child Development, Volume 89, Issue 3, Page 7-109, December 2024.
Abstract In this Monograph, we explored neurocognitive predictors of executive function (EF) development in a cohort of children followed longitudinally from 30 to 54 months of age. We tested predictions of a dynamic field model that explains development in a benchmark measure of EF development, the dimensional change card sort (DCCS) task.
Alexis McCraw, Jacqueline Sullivan, Kara Lowery, Rachel Eddings, Hollis R. Heim, Aaron T. Buss   +5 more
wiley   +1 more source

Downregulation of lncRNA ZFAS1 protects H9c2 cardiomyocytes from ischemia/reperfusion-induced apoptosis via the miR-590-3p/NF-κB signaling pathway

Molecular Medicine Reports, 2020
Long non-coding RNA (lncRNA) ZNFX1 antisense RNA 1 (ZFAS1) is upregulated in acute myocardial infarction; however, the role of ZFAS1 in myocardial ischemia/reperfusion (I/R) injury remains unknown.
Peng Huang, Dongbai Yang, Lianzhi Yu, Yu Shi   +3 more
semanticscholar   +1 more source

Giving a voice to our silent teachers: Whole body donation from the donor perspective at one donation program in the United States

Anatomical Sciences Education, Volume 17, Issue 4, Page 893-908, June 2024.
Abstract Human body donors play a crucial role in anatomical education, research, and clinical skills training, and those interested in anatomical donation may bequeath their bodies to body donation programs (BDPs). The purpose of this study was to evaluate the perspective of body donors on the donation process in order to make recommendations for ...
Lauren K. Bagian, Danielle C. Davis, Ryan C. Parker, Claudia F. Mosley, Joy Y. Balta   +4 more
wiley   +1 more source

miR-590-3p Targets Cyclin G2 and FOXO3 to Promote Ovarian Cancer Cell Proliferation, Invasion, and Spheroid Formation

International Journal of Molecular Sciences, 2019
Ovarian cancer is the leading cause of death from gynecological cancers. MicroRNAs (miRNAs) are small, non-coding RNAs that interact with the 3′ untranslated region (3′ UTR) of target genes to repress their expression.
M. Salem, Yanan Shan, S. Bernaudo, C. Peng   +3 more
semanticscholar   +1 more source

L-Dopa-Decarboxylase (DDC) Is a Positive Prognosticator for Breast Cancer Patients and Epinephrine Regulates Breast Cancer Cell (MCF7 and T47D) Growth In Vitro According to Their Different Expression of Gi- Protein- Coupled Receptors

International Journal of Molecular Sciences, 2020
A coherence between thyroid dysfunction and breast cancer incidence exists. Thyroid hormone metabolites bind to TAAR1 (trace amine-associated receptor 1) and through that modulate the serotonergic and dopaminergic system.
E. Tremmel, C. Kuhn, T. Kaltofen, T. Vilsmaier, D. Mayr, S. Mahner, N. Ditsch, U. Jeschke, A. Vattai   +8 more
semanticscholar   +1 more source