Results 1 to 10 of about 268 (67)

Protective Role of AMPK against PINK1B9 Flies' Neurodegeneration with Improved Mitochondrial Function. [PDF]

open access: yesParkinsons Dis, 2023
Adenosine 5′‐monophosphate‐activated protein kinase (AMPK)’s effect in PTEN‐induced kinase 1 (PINK1) mutant Parkinson’s disease (PD) transgenic flies and the related mechanism is seldom studied. The classic MHC-Gal4/UAS PD transgenic flies was utilized to generate the disease characteristics specifically expressed in flies’ muscles, and Western blot ...
Xiang G   +7 more
europepmc   +2 more sources

Incidence of hypertension in people with HIV who are treated with integrase inhibitors versus other antiretroviral regimens in the RESPOND cohort consortium. [PDF]

open access: yesHIV Med, 2022
Abstract Objective To compare the incidence of hypertension in people living with HIV receiving integrase strand transfer inhibitor (INSTI)‐based antiretroviral therapy (ART) versus non‐nucleoside reverse transcriptase inhibitors (NNRTIs) or boosted protease inhibitors (PIs) in the RESPOND consortium of HIV cohorts.
Byonanebye DM   +27 more
europepmc   +2 more sources

Guidelines for mouse and human DC functional assays

open access: yesEuropean Journal of Immunology, Volume 53, Issue 12, December 2023., 2023
Conventional DC (cDC) represent a heterogenous family of professional antigen‐presenting cells. Basic functions common to all tissue‐resident cDC include antigen uptake, lymph node migration, and naive T cell priming to induce appropriate effector and regulatory T cell responses.
Björn E. Clausen   +45 more
wiley   +1 more source

Deep Learning‐Enabled Multiplexed Point‐of‐Care Sensor using a Paper‐Based Fluorescence Vertical Flow Assay

open access: yesSmall, Volume 19, Issue 51, December 20, 2023., 2023
A multiplexed point‐of‐care serodiagnosis assay is reported to simultaneously quantify three biomarkers of acute cardiac injury. This point‐of‐care sensor includes a paper‐based fluorescence vertical‐flow‐assay processed by a low‐cost mobile reader, which quantifies the target biomarkers using neural networks within <15 min per test using 50 µL of ...
Artem Goncharov   +10 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander   +28 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Transporters

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander   +27 more
wiley   +1 more source

Variability in nutrient composition of the edible long‐horned grasshopper (Ruspolia differens) in Uganda and its potential in alleviating food insecurity

open access: yesFood Science &Nutrition, Volume 11, Issue 6, Page 3558-3574, June 2023., 2023
Long‐horned grasshoppers are consumed in over 21 African countries. Crude protein (28%–45%), crude fat (41%–54%), and energy (582–644 Kj/100 g) of grasshoppers are comparable to that of plant and animal origins. Grasshopper meal could be considered as functional food ingredients capable of supplying adequate essential macro‐ and micronutrients ...
Margaret Kababu   +4 more
wiley   +1 more source

Understanding beliefs, preferences and actions amongst potential body donors

open access: yesAnatomical Sciences Education, Volume 16, Issue 2, Page 224-236, March/April 2023., 2023
Abstract Body donation is a prosocial act providing a unique learning experience to students, ultimately impacting on patient care and science. With an increasing number of training professionals, there is an increasing need for body donors, yet little is understood about donors' beliefs and preferences.
Claire F. Smith   +9 more
wiley   +1 more source

Protecting Earth and Space Industries from Orbital Debris: Implementing the Outer Space Treaty to Fill the Regulatory Vacuum in the FCC's Orbital Debris Guidelines

open access: yesAmerican Business Law Journal, Volume 60, Issue 1, Page 175-229, Spring 2023., 2023
The Outer Space Treaty (OST) is the foundation of all international space regulation. It establishes space as the province of all humankind and promotes its peaceful use and exploration for the benefit and in the interests of all countries. In 2020, the FCC released its “Mitigation of Orbital Debris in the New Space Age” guidelines for commercial ...
Michael B. Runnels
wiley   +1 more source

Commodity risk assessment of Malus domestica plants from Turkey

open access: yesEFSA Journal, Volume 20, Issue 5, May 2022., 2022
Abstract The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation (EU) 2018/2019 as ‘High risk plants, plant products and other objects’. This Scientific Opinion covers plant health risks posed by dormant grafted plants, rootstocks, budwood and ...
EFSA Panel on Plant Health (PLH)   +31 more
wiley   +1 more source

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