Results 21 to 30 of about 212 (69)

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

British Journal of Pharmacology, Volume 176, Issue S1, Page S297-S396, December 2019., 2019
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www ...
Stephen P H Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators, Annie Beuve, Detlev Boison, Peter Brouckaert, John C Burnett, Kathryn Burns, Carmen Dessauer, Andreas Friebe, John Garthwaite, Jürg Gertsch, Nuala Helsby, Angelo A Izzo, Doris Koesling, Michaela Kuhn, Rennolds Ostrom, Andreas Papapetropoulos, Lincoln R Potter, Nigel J Pyne, Susan Pyne, Michael Russwurm, Harald HHW Schmidt, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts   +39 more
wiley   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters

British Journal of Pharmacology, Volume 176, Issue S1, Page S397-S493, December 2019., 2019
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www ...
Stephen P H Alexander, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators, Catriona MH Anderson, Stefan Bröer, Paul Dawson, Bruno Hagenbuch, James R Hammond, Jules Hancox, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, David T Thwaites, Tiziano Verri   +23 more
wiley   +1 more source

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

MedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen, Jiachen Liu, Yinhuai Wang, Zebin Deng, Fei Deng   +4 more
wiley   +1 more source

Increased Matrix Stiffness Promotes Slow Muscle Fibre Regeneration After Skeletal Muscle Injury

Journal of Cellular and Molecular Medicine, Volume 29, Issue 4, February 2025.
ABSTRACT The global prevalence of skeletal muscle diseases has progressively escalated in recent years. This study aimed to explore the potential role of matrix stiffness in the repair mechanisms following skeletal muscle injury. We observed an increase in muscle stiffness, a significant rise in the number of type I muscle fibres and a notable ...
Dongmei Wang, Jiahong Wu, Zeyu Xu, Jinning Jia, Yimei Lai, Zhihua He   +5 more
wiley   +1 more source

Dynamic Field Theory of Executive Function: Identifying Early Neurocognitive Markers

Monographs of the Society for Research in Child Development, Volume 89, Issue 3, Page 7-109, December 2024.
Abstract In this Monograph, we explored neurocognitive predictors of executive function (EF) development in a cohort of children followed longitudinally from 30 to 54 months of age. We tested predictions of a dynamic field model that explains development in a benchmark measure of EF development, the dimensional change card sort (DCCS) task.
Alexis McCraw, Jacqueline Sullivan, Kara Lowery, Rachel Eddings, Hollis R. Heim, Aaron T. Buss   +5 more
wiley   +1 more source

Deep‐Focus Earthquake Mechanisms at the Subducting Nazca Plate (Peru‐Brazil Border): Cold Slab Behavior in a Warm Plate

Earth and Space Science, Volume 11, Issue 10, October 2024.
Abstract We calculate focal mechanisms and centroid depths for deep‐focus earthquakes (DFEs) along the Peru‐Brazil border. We obtained a total of 28 focal solutions for events with magnitudes between 4.2 and 7.5 Mw and occurring between 2014 and 2022.
G. S. Leite Neto, J. Julià, G. A. Prieto   +2 more
wiley   +1 more source

The merits of securities litigation and corporate reputation

Contemporary Accounting Research, Volume 41, Issue 1, Page 424-458, Spring 2024.
Abstract We explore how securities litigation affects corporate reputation. Experts remain concerned that nonmeritorious securities class actions—those that will be dismissed or settled for nuisance amounts—cause reputational damage. Although several prior studies show reputational costs for nonmeritorious cases, they generally use indirect measures ...
Dain C. Donelson, Antonis Kartapanis, Christopher G. Yust   +2 more
wiley   +1 more source

UEG Week 2025 Moderated Posters

United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley   +1 more source

“Abstracts of the 78th Annual Meeting of the Japanese Cancer Association; 2019 Sept 26‐28; Kyoto, Japan” as Cancer Science, Supplement 1, Vol 110 (2019)

, 2019
Cancer Science, Volume 110, Issue S1, Page 1-1208, December 2019.
wiley   +1 more source

In vivo CRISPR screening reveals epigenetic regulators of hepatobiliary plasticity. [PDF]

Genes Dev
Sussman JH, Cure HW, Yuan S, Ito K, Asangani IA, Garcia BA, Stanger BZ, Katsuda T.   +7 more
europepmc   +1 more source