Results 1 to 10 of about 368 (67)

Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]

open access: yesMedComm (2020)
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Li G   +13 more
europepmc   +2 more sources

Guidelines for mouse and human DC functional assays

open access: yesEuropean Journal of Immunology, Volume 53, Issue 12, December 2023., 2023
Conventional DC (cDC) represent a heterogenous family of professional antigen‐presenting cells. Basic functions common to all tissue‐resident cDC include antigen uptake, lymph node migration, and naive T cell priming to induce appropriate effector and regulatory T cell responses.
Björn E. Clausen   +45 more
wiley   +1 more source

Prodromal Parkinson's disease and the catecholaldehyde hypothesis: Insight from olfactory bulb organotypic cultures

open access: yesThe FASEB Journal, Volume 37, Issue 12, December 2023., 2023
Olfactory dysfunction is one of the most prevalent symptoms of Parkinson's disease preceding clinical onset by up to a decade. However, PD models focus mainly on motor symptoms and nigrostriatal degeneration. Here, we characterize cultured olfactory bulb organotypic slices and cells and explore the effect of DOPAL, a metabolite of dopamine.
Enrico Bagnoli   +6 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander   +28 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Transporters

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander   +27 more
wiley   +1 more source

In‐depth proteomic analysis reveals unique subtype‐specific signatures in human small‐cell lung cancer

open access: yesClinical and Translational Medicine, Volume 12, Issue 9, September 2022., 2022
The first mass spectrometry–based proteomic analysis on small‐cell lung cancer (SCLC) cell lines, reporting unique proteomic profiles of its proposed molecular subtypes. SCLC subgroups detected by proteomics are consistent with mRNA‐based subtypes.
Beáta Szeitz   +20 more
wiley   +1 more source

Ribcage Morphology in Native South American Populations From Different Altitudes: Insights From a Global Comparative Framework

open access: yesAmerican Journal of Human Biology, Volume 38, Issue 2, February 2026.
ABSTRACT Objectives Altitude shapes human morphology as highland populations must cope with cold and hypoxic environments. Although Andean highlanders have been proposed to exhibit larger and deeper ribcages, this idea is mainly based on research using disarticulated skeletal elements or non‐South American controls. The objective of this research is to
J. M. López‐Rey   +9 more
wiley   +1 more source

MSAA‐MSDA: A Multi‐Source Domain Adaptation Method for Remote Sensing Scene Classification Based on Multi‐Scale Attention Aggregation

open access: yesIET Image Processing, Volume 20, Issue 1, January/December 2026.
ABSTRACT Remote sensing scene classification is often challenged by domain shifts arising from variations in regions and sensor types, which can significantly degrade performance when models are applied to unlabelled target domains. Multi‐source domain adaptation (MSDA) leverages multiple labelled source domains to improve generalization, but its ...
Wei Dai   +4 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

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