Results 11 to 20 of about 316 (65)
Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]
MedComm (2020)Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Li G +13 more
europepmc +2 more sources
Allelopathy as a Strategy for Biological Invasion: Calotropis procera and Its Impact on Plant Succession. [PDF]
Chem BiodiversStages of the study on the allelopathic potential of Calotropis procera (Aiton) W. T. Aiton. The image shows the collection of plant material, the decomposition of organic matter, the identification of bioactive compounds, and the effects on the germination of Handroanthus impetiginosus (Mart. ex DC.) Mattos.
de Alcântara BM +7 more
europepmc +2 more sources
Mild/moderate phenotypes in AADC deficiency: Focus on the aromatic amino acid decarboxylase protein. [PDF]
J Inherit Metab DisAbstract AADC deficiency is a severe neurometabolic inherited rare disorder due to the absence or decrease of dopamine and serotonin levels, causing deep motor and neurodevelopmental impairments. The disease is often fatal in the first decade of life, and pharmacological treatments (dopamine agonists, pyridoxine, and monoamine oxidase inhibitors as the
Bisello G +3 more
europepmc +2 more sources
Guidelines for mouse and human DC functional assays
European Journal of Immunology, Volume 53, Issue 12, December 2023., 2023 Conventional DC (cDC) represent a heterogenous family of professional antigen‐presenting cells. Basic functions common to all tissue‐resident cDC include antigen uptake, lymph node migration, and naive T cell priming to induce appropriate effector and regulatory T cell responses.
Björn E. Clausen +45 more
wiley +1 more source
Methylphosphonate Is Utilized by Commensal Microbiota of Macroalgae in the Oligotrophic Sargasso Sea
Journal of Geophysical Research: Oceans, Volume 128, Issue 12, December 2023., 2023 Abstract The essential nutrient phosphorus is biologically scarce in the Sargasso Sea, yet the pelagic macroalgae Sargassum, for which this area of the North Atlantic Ocean is named, thrives. We tested the hypothesis that Sargassum holobionts utilize methylphosphonate (MPn) as an alternative source of phosphorus, finding lysis liberated phosphonate ...
D. D. Cox +3 more
wiley +1 more source
Guidelines for mouse and human DC generation
European Journal of Immunology, Volume 53, Issue 11, November 2023., 2023 The article on DC generation is part of the DC Guidelines article collection providing methods for the isolation of mouse and human cellular sources that can be cultured with different growth factors to generate the known subsets of DC. Abstract This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state ...
Manfred B. Lutz +25 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: Enzymes
British Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +28 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: Transporters
British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander +27 more
wiley +1 more source
Recent advances in sea cucumber peptide: Production, bioactive properties, and prospects
Food Frontiers, Volume 4, Issue 1, Page 131-163, March 2023., 2023 Abstract Sea cucumber is a precious and nutritious food with abundant protein and other bioactive compounds, among which sea cucumber peptide (SCP) exhibits many beneficial functions. Although research on the development of SCP is attracting more attention, the ability to translate these new findings into industrial practice and new products remains ...
Jiacong Man +3 more
wiley +1 more source
Monitoring regional astrocyte diversity by cell type‐specific proteomic labeling in vivo
Glia, Volume 71, Issue 3, Page 682-703, March 2023., 2023 Main Points In vivo metabolic labeling enables astrocyte‐specific proteome analysis in four brain regions by LC–MS/MS. Biological processes or key astrocytic proteins show subtle variances between brain regions and region‐specific disease associations. Abstract Astrocytes exhibit regional heterogeneity in morphology, function and molecular composition ...
Priyadharshini Prabhakar +9 more
wiley +1 more source