Results 11 to 20 of about 202 (67)
The Concise Guide to PHARMACOLOGY 2023/24: Transporters
British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander +27 more
wiley +1 more source
The Patent Examiner Sweepstakes
American Business Law Journal, Volume 60, Issue 3, Page 599-650, Fall 2023., 2023 This article presents evidence that patent value varies with random examiner assignment at the U.S. Patent Office. Prior work analyzed firm growth as a function of review by “easy” examiners who grant patents at a high rate. The current research looks past whether a patent is granted and instead focuses on how assignment to an “easy” or “hard” examiner
W. Michael Schuster
wiley +1 more source
Hepatology Communications, Volume 6, Issue 11, Page 3036-3051, November 2022., 2022 We determined the prevalence of both liver steatosis and liver fibrosis in a HIV cohort in Ghana using a portable FibroScan, and we interpreted the data within a broad context, including measurements that are not part of routine HIV care in Kumasi. We identified two main reasons for concern: (1) metabolic syndrome was common and a predictor of liver ...
Giovanni Villa +10 more
wiley +1 more source
Enzymology of the pathway for ATP production by arginine breakdown
The FEBS Journal, Volume 288, Issue 1, Page 293-309, January 2021., 2021 In cells, the breakdown of arginine to ornithine and ammonium ion plus carbon dioxide is coupled to the generation of ATP. The proteins involved in arginine breakdown and ATP production include the following: arginine deiminase, ornithine transcarbamoylase, carbamate kinase, and an arginine/ornithine antiporter.
Tjeerd Pols +4 more
wiley +1 more source
BioMed Research International, Volume 2021, Issue 1, 2021., 2021 Atopic dermatitis (AD) is a chronic, inflammatory skin disease with an eczematous rash and itching. Due to undesired adverse effects of traditional systemic treatment, there is still an unmet need for safe and effective long‐term therapy for refractory AD. As our understanding of the pathogenesis underlying AD grows, novel treatments targeting specific
Hong-jiao Qi +2 more
wiley +1 more source
High-mobility-group protein 2 regulated by microRNA-127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells. [PDF]
Hepatol Commun, 2017 High‐mobility‐group protein 2 (HMGB2) expression is up‐regulated in human liver cancer; however, little is known about its regulatory function. Here, we establish HMGB2 as a new modulator of the pluripotency of mouse embryonic stem cells. Similar to octamer‐binding transcription factor 4 (OCT4) and sex‐determining region Y‐box 2 (SOX2), HMGB2 protein ...
Zhao Y +6 more
europepmc +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Update of the Xylella spp. host plant database
EFSA Journal, Volume 16, Issue 9, September 2018., 2018 Abstract Following a request from the European Commission, EFSA periodically updates the database on the host plants of Xylella spp. While previous editions of the database (2015 and 2016) dealt with the species Xylella fastidiosa only, this database version addresses the whole genus Xylella, including therefore both species X.
European Food Safety Authority (EFSA)
wiley +1 more source
The Plant Journal, Volume 123, Issue 6, September 2025.SUMMARY Carboxysomes are bacterial microcompartments that encapsulate Rubisco and are a core component of the cyanobacterial carbon concentration mechanism (CCM). While carboxysome number, size, and spatial organization vary in different environmental conditions (CO2, light availability, redox state, temperature, and light quality), the molecular ...
María Santos‐Merino +4 more
wiley +1 more source