Results 11 to 20 of about 159 (64)
Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis. [PDF]
Adv Sci (Weinh)Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Alves F +17 more
europepmc +2 more sources
An evolutionarily distinct ringed seal in the Ilulissat Icefjord
Molecular Ecology, Volume 32, Issue 22, Page 5932-5943, November 2023., 2023 Abstract The Earth's polar regions are low rates of inter‐ and intraspecific diversification. An extreme mammalian example is the Arctic ringed seal (Pusa hispida hispida), which is assumed to be panmictic across its circumpolar Arctic range. Yet, local Inuit communities in Greenland and Canada recognize several regional variants; a finding supported ...
Aqqalu Rosing‐Asvid +15 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: Transporters
British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander +27 more
wiley +1 more source
Journal of the International AIDS Society, Volume 26, Issue 6, June 2023., 2023 Abstract Introduction Integrase strand transfer inhibitor (INSTI)‐containing antiretroviral therapy (ART) has been associated with weight gain, though there is limited information on associations between ART‐related weight gain and cardiometabolic outcomes among people living with HIV‐1 (PLWH). We, therefore, evaluated risks of incident cardiometabolic
Peter F. Rebeiro +7 more
wiley +1 more source
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters
British Journal of Pharmacology, Volume 178, Issue S1, Page S412-S513, October 2021., 2021 The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets ...
Stephen P H Alexander +24 more
wiley +1 more source
Burden of arrhythmia in hospitalized HIV patients
Clinical Cardiology, Volume 44, Issue 1, Page 66-77, January 2021., 2021 Abstract Background The improved life expectancy observed in patients living with human immunodeficiency virus (HIV) infection has made age‐related cardiovascular complications, including arrhythmias, a growing health concern. Hypothesis We describe the temporal trends in frequency of various arrhythmias and assess impact of arrhythmias on hospitalized
Anas A. Abudan +10 more
wiley +1 more source
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters
British Journal of Pharmacology, Volume 176, Issue S1, Page S397-S493, December 2019., 2019 The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www ...
Stephen P H Alexander +23 more
wiley +1 more source
Update of the Xylella spp. host plant database
EFSA Journal, Volume 16, Issue 9, September 2018., 2018 Abstract Following a request from the European Commission, EFSA periodically updates the database on the host plants of Xylella spp. While previous editions of the database (2015 and 2016) dealt with the species Xylella fastidiosa only, this database version addresses the whole genus Xylella, including therefore both species X.
European Food Safety Authority (EFSA)
wiley +1 more source
Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.Cell therapies often fail in the clinic due to poor in vivo persistence. In this study, we developed a 3D bioprinting strategy using continuous liquid interface production (CLIP) to generate cell therapy delivery systems. We provide a robust characterization of this new technique, demonstrating the positive effect of CLIP bioprinting on the efficacy of
Lauren Kass +6 more
wiley +1 more source
Advanced Functional Materials, Volume 34, Issue 43, October 22, 2024.This review emphasizes the critical role of molecular modeling in metal‐organic framework (MOF) research. It explores the use of density functional theory, Monte Carlo, and molecular dynamics methods for obtaining atomistic‐level insights into diverse MOF phenomena and properties. Additionally, it discusses machine learning techniques as valuable tools
Filip Formalik +4 more
wiley +1 more source