Results 21 to 30 of about 26,500 (113)

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Protective effect of green perilla-derived chalcone derivative DDC on amyloid β protein-induced neurotoxicity in primary cortical neurons.

Biological and Pharmaceutical Bulletin, 2019
Amyloid β protein (Aβ) causes neurotoxicity and cognitive impairment in Alzheimer's disease (AD). Oxidative stress is closely related to the pathogenesis of AD.
M. Iwasaki, Naotaka Izuo, Yasuhiko Izumi, Yuki Takada‐Takatori, A. Akaike, T. Kume   +5 more
semanticscholar   +1 more source

Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathy

Scientific Reports, 2018
Kupffer cells (KCs) are key players in maintaining tissue homeostasis and are involved in various liver diseases. However, the roles of KCs in the pathogenesis of cholangiopathy are largely unknown.
Leila Jemail, Masashi Miyao, H. Kotani, C. Kawai, Hirozo Minami, H. Abiru, Keiji Tamaki   +6 more
semanticscholar   +1 more source

Leukocyte count and new‐onset diabetes mellitus in people with HIV: A longitudinal study

HIV Medicine, Volume 26, Issue 10, Page 1585-1599, October 2025.
Abstract Objectives The risk of diabetes mellitus (DM) is increased in people with HIV. Chronic inflammation contributes to DM risk. High leukocytes are associated with DM in the general population, but in people with HIV, evidence of a leukocyte–DM association is limited. Methods We included participants of the Swiss HIV Cohort Study with new‐onset DM
Sophia C. Meyer, Zoe Klein, Isabella C. Schoepf, Christian W. Thorball, Marco Labarile, Neeltje A. Kootstra, Peter Reiss, Lene Ryom, Dominique L. Braun, Maria C. Thurnheer, Catia Marzolini, Christian R. Kahlert, Enos Bernasconi, Matthias Cavassini, Annalisa Marinosci, Jacques Fellay, Huldrych F. Günthard, Roger D. Kouyos, Bruno Ledergerber, Philip E. Tarr, the Swiss HIV Cohort Study, I Abela, K Aebi‐Popp, A Anagnostopoulos, M Battegay, E Bernasconi, DL Braun, HC Bucher, A Calmy, M Cavassini, A Ciuffi, G Dollenmaier, M Egger, L Elzi, J Fehr, J Fellay, H Furrer, CA Fux, HF Günthard, A Hachfeld, D Haerry, B Hasse, HH Hirsch, M Hoffmann, I Hösli, M Huber, D Jackson‐Perry, patient representatives, CR Kahlert, O Keiser, T Klimkait, RD Kouyos, H Kovari, K Kusejko, N Labhardt, K Leuzinger, B Martinez de Tejada, C Marzolini, KJ Metzner, N Müller, J Nemeth, D Nicca, J Notter, P Paioni, G Pantaleo, M Perreau, A Rauch, L Salazar‐Vizcaya, P Schmid, R Speck, M Stöckle, P Tarr, A Trkola, G Wandeler, M Weisser, S. Yerly   +75 more
wiley   +1 more source

A comprehensive survey of crowd density estimation and counting

IET Image Processing, Volume 19, Issue 1, January/December 2025.
This paper provides a comprehensive survey of crowd density estimation and counting approaches, categorizing them into traditional and deep learning‐based approaches. It focuses on analysing deep learning‐based methods, discusses training and evaluation details, and compares the performance of classical models. The paper also discusses future prospects,
Mingtao Wang, Xin Zhou, Yuanyuan Chen
wiley   +1 more source

USP38, FREM3, SDC1, DDC, and LOC727982 Gene Polymorphisms and Differential Susceptibility to Severe Malaria in Tanzania

Journal of Infectious Diseases, 2015
Populations exposed to Plasmodium falciparum infection develop genetic mechanisms of protection against severe malarial disease. Despite decades of genetic epidemiological research, the sickle cell trait (HbAS) sickle cell polymorphism, ABO blood group ...
A. Manjurano, N. Sepúlveda, Behzad Nadjm, G. Mtove, Hannah Wangai, C. Maxwell, R. Olomi, Hugh Reyburn, C. Drakeley, E. Riley, T. Clark   +10 more
semanticscholar   +1 more source

Oral health status of institutionalized older adults receiving domiciliary dental care: A cross‐sectional retrospective study

Special Care in Dentistry, Volume 44, Issue 5, Page 1444-1455, September 2024.
Abstract Aim This study aimed to evaluate the oral health of care‐dependent institutionalized older adults receiving domiciliary dental care. Methods and Results Dental health records of institutionalized adults receiving regular domiciliary dental care were examined (observation period: 5 years).
Philipp Allenspach, Murali Srinivasan
wiley   +1 more source

IL-10 mediated by herpes simplex virus vector reduces neuropathic pain induced by HIV gp120 combined with ddC in rats

Molecular Pain, 2014
BackgroundHIV-associated sensory neuropathy affects over 50% of HIV patients and is a common peripheral nerve complication of HIV infection and highly active antiretroviral therapy (HAART). Evidence shows that painful HIV sensory neuropathy is influenced
Wenwen Zheng, Wan Huang, Shue Liu, R. Levitt, K. Candiotti, D. Lubarsky, S. Hao   +6 more
semanticscholar   +1 more source

Comparative Analysis and Modeling of the Severity of Steatohepatitis in DDC-Treated Mouse Strains

PLoS ONE, 2014
Background Non-alcoholic fatty liver disease (NAFLD) has a broad spectrum of disease states ranging from mild steatosis characterized by an abnormal retention of lipids within liver cells to steatohepatitis (NASH) showing fat accumulation, inflammation ...
V. Pandey, M. Sultan, K. Kashofer, M. Ralser, V. Amstislavskiy, J. Starmann, I. Osprian, C. Grimm, Hendrik Hache, M. Yaspo, H. Sültmann, M. Trauner, H. Denk, K. Zatloukal, H. Lehrach, C. Wierling   +15 more
semanticscholar   +1 more source

Indigenous Peoples in the U.S., Sovereign Nations, and the DDC

, 2015
Claims of bias within the Dewey Decimal Classification (DDC) system in its treatment of indigenous peoples in the U.S. focus on marginalization through ghettoization, historicization, diasporization, and missing topics, such as the status of indigenous ...
Rebecca Green
semanticscholar   +1 more source