Results 31 to 40 of about 40,231 (113)

Circular RNA MAT2B Induces Colorectal Cancer Proliferation via Sponging miR-610, Resulting in an Increased E2F1 Expression

Cancer Management and Research, 2020
Purpose Recently, studies have demonstrated that a novel circular RNA (circRNA), circMAT2B, can promote cell proliferation and can thus contribute to the growth and development of hepatocellular carcinoma.
Jian Zhao, Li Chen
semanticscholar   +1 more source

Northern Schools and Lemon’s Forgotten Segregation Claim

, 2022
Journal of Supreme Court History, Volume 47, Issue 2, Page 179-196, July 2022.
Catherine Ward
wiley   +1 more source

Nrf2 Ameliorates DDC-Induced Sclerosing Cholangitis and Biliary Fibrosis and Improves the Regenerative Capacity of the Liver.

Toxicological Sciences, 2019
The Nrf2 pathway protects against oxidative stress and induces regeneration of various tissues. Here, we investigated whether Nrf2 protects from sclerosing cholangitis and biliary fibrosis and simultaneously induces liver regeneration.
A. Fragoulis, J. Schenkel, M. Herzog, Tim Schellenberg, H. Jahr, T. Pufe, C. Trautwein, T. Kensler, K. Streetz, C. Wruck   +9 more
semanticscholar   +1 more source

Analysis of Expression and Functional Activity of Aromatic L-Amino Acid Decarboxylase (DDC) and Serotonin Transporter (SERT) as Potential Sources of Serotonin in Mouse Ovary

International Journal of Molecular Sciences, 2019
The origin of serotonin in the ovary is the key question for understanding mechanisms of serotonergic regulation of reproductive function. We performed a study of the expression and functional activity of the serotonin transporter (SERT) and the enzyme ...
D. A. Nikishin, N. M. Alyoshina, M. Semenova, Y. B. Shmukler   +3 more
semanticscholar   +1 more source

UEG Week 2023 Moderated Posters

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley   +1 more source

Multiple genetic variants at the SLC30A8 locus affect local super‐enhancer activity and influence pancreatic β‐cell survival and function

The FASEB Journal, Volume 38, Issue 8, 30 April 2024.
GWAS‐identified SLC30A8 locus contains an islet super‐enhancer cluster. This super‐enhancer cluster regulates the expression of not only the SLC30A8 gene but also multiple other genes (UTP23, RAD21, MED30, and EXT1) which are involved in fundamental cellular machineries.
Ming Hu, Innah Kim, Ignasi Morán, Weicong Peng, Orien Sun, Amélie Bonnefond, Amna Khamis, Sílvia Bonàs‐Guarch, Philippe Froguel, Guy A. Rutter   +9 more
wiley   +1 more source

Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathy

Scientific Reports, 2018
Kupffer cells (KCs) are key players in maintaining tissue homeostasis and are involved in various liver diseases. However, the roles of KCs in the pathogenesis of cholangiopathy are largely unknown.
Leila Jemail, Masashi Miyao, H. Kotani, C. Kawai, Hirozo Minami, H. Abiru, Keiji Tamaki   +6 more
semanticscholar   +1 more source

Unwinding NFTs in the shadow of IP law

American Business Law Journal, Volume 61, Issue 1, Page 31-55, Spring 2024.
Abstract Amid the surge of intellectual property (IP) disputes surrounding non‐fungible tokens (NFTs), some scholars have advocated for the application of personal property or sales law to regulate NFT minting and transactions, contending that IP laws unduly hinder the development of the NFT market. This Article counters these proposals and argues that
Runhua Wang, Jyh‐An Lee, Jingwen Liu
wiley   +1 more source

Mid‐Holocene rainfall seasonality and ENSO dynamics over the south‐western Pacific

The Depositional Record, Volume 10, Issue 1, Page 176-194, February 2024.
We provide a layer counted and U/Th‐dated record of mid‐Holocene rainfall and ENSO changes in the south‐western Pacific using a stalagmite from Niue Island. We combine oxygen and carbon isotope ratios with trace elements and greyscale data to infer changes in local infiltration at seasonal to multi‐decadal timescales.
Cinthya Nava‐Fernandez, Tobias Braun, Chelsea L. Pederson, Bethany Fox, Adam Hartland, Ola Kwiecien, Sebastian N. Höpker, Stefano Bernasconi, Madalina Jaggi, John Hellstrom, Fernando Gázquez, Amanda French, Norbert Marwan, Adrian Immenhauser, Sebastian F. M. Breitenbach   +14 more
wiley   +1 more source

Protective effect of green perilla-derived chalcone derivative DDC on amyloid β protein-induced neurotoxicity in primary cortical neurons.

Biological and Pharmaceutical Bulletin, 2019
Amyloid β protein (Aβ) causes neurotoxicity and cognitive impairment in Alzheimer's disease (AD). Oxidative stress is closely related to the pathogenesis of AD.
M. Iwasaki, Naotaka Izuo, Yasuhiko Izumi, Yuki Takada‐Takatori, A. Akaike, T. Kume   +5 more
semanticscholar   +1 more source