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Therapeutic Targeting of DNA Damage Repair in the Era of Precision Oncology and Immune Checkpoint Inhibitors [PDF]

open access: yesJournal of Immunotherapy and Precision Oncology, 2023
Cancer manifestation is a multistep process involving accumulation of various genetic and epigenetic changes that results in oncogenic “hallmarks of cancer” processes including genomic instability.
Curtis A. Clark, Eddy S. Yang
doaj   +1 more source

Local Understandings of Disarmament-Demobilization-Reintegration (DDR): Former Combatants’ Perspectives on DDR in Colombia

open access: yesAlternatif Politika, 2023
DDR processes, the design of which follows technical knowledge produced by international organizations and programs, have become a standard way for addressing the process of armed groups’ transition from armed to civilian life. However, the components of
Esra Dilek, Başar Baysal
doaj   +1 more source

Perbandingan Numeric Rating Scale Nyeri Pascaoperasi Kolesistektomi Laparoskopik Antara Blokade Erector Spinae Plane dan Petidin Intravena

open access: yesJurnal Anestesi Perioperatif, 2021
Nyeri pascaoperasi harus diatasi dengan baik. Berbagai metode analgetik dilakukan untuk mengatasi nyeri pascaoperasi kolesistektomi laparoskopik, namun tidak ada yang ideal dalam menangani nyeri pascaoperasi.
Arrys Prabowo   +2 more
doaj   +1 more source

Educación para excombatientes en el posconflicto. Un estado del arte de las propuestas educativas y de intervención con excombatientes

open access: yesCiudad Paz-ando, 2022
El propósito de este artículo es indagar sobre las investigaciones que se han hecho respecto a la educación para excombatientes a nivel nacional e internacional. Se hallaron tres grandes tendencias: 1.
Rober Fernando Buitrago Castellanos
doaj   +1 more source

Comment on the Dependence of R□ and Current Noise on Grain Size in Thick Film Resistors (TFR's)

open access: yesActive and Passive Electronic Components, 1985
The heterogeneous structure of TFR's results in high resistivities and high current noise. Accepting models of conduction in TFR's, according to which the resistivity is determined by a resistance independent of bulk-resistivity of a metallic-like ...
M. Wolf, F. Müller, H. Hemschik
doaj   +1 more source

About the Influence of SiO2 on the Temperature Behaviour of Ruthenate Based Thick Film Resistors

open access: yesActive and Passive Electronic Components, 1987
Substituting glass by SiO2 in thick film resistors results in a small increase of R□, a decrease of dR□/dT and an increase of d2R□/dT2 (at room temperature).
I. Storbeck, M. Wolf
doaj   +1 more source

Synthese und Eigenschaften eines neuen heterozyklischen Systems, des Imidazo[2.1-c]-as-triazins

open access: yesCHIMIA, 1969
By ring fission of 2-amino-3-phenacyl-oxazoliumhalogenides with hydrazines produces in a fast reaction the new system of 1.4-dihydroimidazo[2.1-c]-as-triazines. The reactivity and characteristic fluorescence properties of these compounds are described.
A. Hetzheim, H. Pusch
doaj   +1 more source

Untersuchungen zum Reaktionsverhalten von N,N-disubstituierten Thioharnstoffen gegenüber Dicyanimid (DCI)

open access: yesCHIMIA, 1974
N,N-disubstituted thioureas react with dicyanimide in a simple reaction to form derivatives of the 4H-1.3.5-thiadiazine. The N,N-dimethyl-, N,N-diethyl- and N,N-di-n-propyl-thiourea react under formation of derivatives of S, S'-bis-guanyl ...
Eberhard Fischer   +2 more
doaj   +1 more source

On an initial-boundary value problem for the nonlinear Schrödinger equation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1979
We study an initial-boundary value problem for the nonlinear Schrödinger equation, a simple mathematical model for the interaction between electromagnetic waves and a plasma layer.
Herbert Gajewski
doaj   +1 more source

Über Reaktionen von Dicyanimid (DCI) mit N,N'-disubstituierten Thioharnstoffen

open access: yesCHIMIA, 1974
The reaction of dicyanimide with symmetrical disubstituted thioureas in absolute alcohol in presence of hydrogen chloride gives in good yields derivatives of the 1.3.5-thiadiazine.
Eberhard Fischer   +2 more
doaj   +1 more source

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