Results 181 to 190 of about 1,286,932 (258)

A Method for Efficient De-identification of DICOM Metadata and Burned-in Pixel Text. [PDF]

J Imaging Inform Med
Macdonald JA, Morgan KR, Konkel B, Abdullah K, Martin M, Ennis C, Lo JY, Stroo M, Snyder DC, Bashir MR.   +9 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Documenting the de-identification process of clinical and imaging data for AI for health imaging projects. [PDF]

Insights Imaging
Kondylakis H, Catalan R, Alabart SM, Barelle C, Bizopoulos P, Bobowicz M, Bona J, Fotiadis DI, Garcia T, Gomez I, Jimenez-Pastor A, Karatzanis G, Lekadir K, Kogut-Czarkowska M, Lalas A, Marias K, Marti-Bonmati L, Munuera J, Nikiforaki K, Pelissier M, Prior F, Rutherford M, Saint-Aubert L, Sakellariou Z, Seymour K, Trouillard T, Votis K, Tsiknakis M.   +27 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Enhancing Catchment Area Tools: A De-Identification Method for Integrating Clinical Trial Data with Cancer InFocus. [PDF]

Prev Oncol Epidemiol
Antonio D, Burus T, Manning TM, Gurley MJ, Di Salvo G, Heneche JA, Passaglia C, Kocherginsky M, Simon MA.   +8 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Examining the Generalizability of Pretrained De-identification Transformer Models on Narrative Nursing Notes. [PDF]

Appl Clin Inform
Chen F, Bokhari SMA, Cato K, Gürsoy G, Rossetti S.   +4 more
europepmc   +1 more source

De-identification of electronic health record using neural network. [PDF]

Sci Rep, 2020
Ahmed T, Aziz MMA, Mohammed N.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source