De-risking primary prevention: role of imaging [PDF]
Therapeutic Advances in Cardiovascular Disease, 2021 Atherosclerotic cardiovascular disease (ASCVD) is a common disease among the general population, and includes four major areas: (1) coronary heart disease (CHD), manifested by stable angina, unstable angina, myocardial infarction (MI), heart failure, and
Ahmed M. Shafter +3 more
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Text Mining for U.S. Pension De-Risking Analysis
Risks, 2022 In the past 30 years, as sponsors of defined benefit (DB) pension plans were facing more severe underfunding challenges, pension de-risking strategies have become prevalent for firms with DB plans to reduce pension-related risks.
Ruilin Tian, Limin Zhang
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Trimming tiers - Motivations and means for de-risking select agents [PDF]
Frontiers in Bioengineering and BiotechnologyIn the United States, pathogens and toxins that pose a significant threat to public health are regulated via the Select Agents and Toxins list (SATL).
Elizabeth Wells +2 more
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De-risking vaccine development: lessons, challenges, and prospects [PDF]
npj VaccinesVaccine development is long and costly. Technical, clinical, regulatory, and manufacturing risks throughout the development cycle hampered manufacturers’ efforts towards more challenging and financially less rewarding targets, with profound implications ...
Vega Masignani +4 more
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Data-Driven Automated Cardiac Health Management with Robust Edge Analytics and De-Risking [PDF]
Sensors, 2019 Remote and automated healthcare management has shown the prospective to significantly impact the future of human prognosis rate. Internet of Things (IoT) enables the development and implementation ecosystem to cater the need of large number of relevant ...
Arijit Ukil +2 more
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Challenges in Diagnosis of COVID-19 Pneumonia under Ocrelizumab and De-Risking Strategies in Multiple Sclerosis—The Elephant Is (Still) in the Room [PDF]
MicroorganismsSevere SARS-CoV-2 infections may still be observed in people bearing risk factors, such as the use of anti-CD20 monoclonal antibodies (mAbs), which are adopted in several autoimmune disorders including multiple sclerosis (MS).
Alice Mariottini +3 more
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De-risking fault leakage risk and containment integrity for subsurface storage applications [PDF]
iScienceSummary: The subsurface is pivotal in the energy transition, for the sequestration of CO2 and energy storage. It is crucial to understand to what extent geological faults may form leakage pathways that threaten the containment integrity of these projects.
Kevin Bisdom, Alvin W. Chan
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COVID-19 lockdown: de-risking exit by protecting the lung with leukaemia inhibitory factor (LIF) [PDF]
Medicine in Drug Discovery, 2020 There are two key needs in COVID-19 management: (i) to reduce SARS-CoV-2 viral infection rate; and (ii) to reduce death rate of those infected - the subject of this commentary.
Su M. Metcalfe
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Reverse translation of adverse event reports paves the way for de-risking preclinical off-targets [PDF]
eLife, 2017 The Food and Drug Administration Adverse Event Reporting System (FAERS) remains the primary source for post-marketing pharmacovigilance. The system is largely un-curated, unstandardized, and lacks a method for linking drugs to the chemical structures of ...
Mateusz Maciejewski +6 more
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De-risking strategy: Longevity spread buy-in
Insurance: Mathematics and Economics, 2018 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Marilena Sibillo +2 more
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