Wave fluctuations near a de Sitter brane in an anti-de Sitter universe
Comptes Rendus. Mathématique, 2015 We investigate the Klein–Gordon equation in the past causal domain of a de Sitter brane imbedded in an anti-de Sitter bulk. We solve the global mixed hyperbolic problem. We prove that any finite energy solution can be expressed as a Kaluza–Klein tower that is a superposition of free fields in the Steady State Universe, of which we study the asymptotic ...
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
From the Janis–Newman–Winicour Naked Singularities to the Einstein–Maxwell Phantom Wormholes
UniverseThe Janis–Newman–Winicour spacetime corresponds to a static spherically symmetric solution of Einstein equations with the energy momentum tensor of a massless quintessence field. It is understood that the spacetime describes a naked singularity.
Changjun Gao, Jianhui Qiu
doaj +1 more source
Detecting the Curvature of de Sitter Universe with Two Entangled Atoms. [PDF]
Sci Rep, 2016 Tian Z +4 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
2 + 1 dimensional de Sitter universe emerging from the gauge structure of a nonlinear quantum system. [PDF]
Sci Rep, 2017 Kam CF, Liu RB.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Aether, dark energy and string compactifications. [PDF]
Philos Trans A Math Phys Eng Sci, 2022 Townsend PK.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source