TNF Pathway‐Mediated Tolerogenic T‐Cell Trajectory Driven by Allergen Immunotherapy
The study shows that AIT re‐establishes local immune equilibrium by restoring Th17/Treg balance, while circulating Th17 cells remain functionally impaired. The transition from pro‐inflammatory Th17 to regulatory T cell states during AIT identifies Tr17 cells as an intermediate cell population.
Helen S. Charles +20 more
wiley +1 more source
Identification of core genes mediating the association between obesity and hepatocellular carcinoma: A bioinformatics study based on mitochondrial metabolism and immune pathways. [PDF]
Li X, Min R.
europepmc +1 more source
HOPE has improved outcomes in ECD liver transplantation and allowed the safe utilization of increasingly marginal grafts with favorable results. ABSTRACT Background The advent of machine perfusion (MP) has significantly improved post‐liver transplantation (post‐LT) outcomes, potentially enabling the use of increasingly marginal grafts and expanding the
Gerti Dajti +16 more
wiley +1 more source
Silicon wafers outperform batteries: efficiency heterogeneity and policy effects in China's photovoltaic industry. [PDF]
Li WQ, Liu HL, Liu XY, Ren FR.
europepmc +1 more source
Abstract This study investigates whether prior exposure to natural disasters influenced individual compliance with non‐pharmaceutical interventions (NPIs), specifically lockdown measures, during the Corona Virus Infectious Disease 2019 (COVID‐19) pandemic. Focusing on the Marche region of Italy, which experienced a severe earthquake in 2016, we exploit
Vincenzo Alfano +2 more
wiley +1 more source
Age differences in endocannabinoid tone are ameliorated after recent cannabis use. [PDF]
Morris AWJ +6 more
europepmc +1 more source
New biosensors and transgenic mice for multiplex cGMP imaging
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters +6 more
wiley +1 more source
Integrated humoral and inflammatory signatures predict outcomes in severe COVID-19: a 14-day longitudinal analysis. [PDF]
Ibiapina HNS +23 more
europepmc +1 more source
Environmentally adjusted productivity growth and shadow prices for dairy farms
Abstract We estimate the environmentally adjusted productivity growth and shadow price for Ontario dairy farms. We use an input‐oriented directional distance function and farm‐level data from 2000 to 2020. First, we find that while GHG emissions per cow increase with higher milk yields, emission intensity decreases as milk yield per cow increases.
Bibek Dahal +2 more
wiley +1 more source
Development of a future prediabetes risk assessment model for individuals with normal glucose levels using data envelopment analysis. [PDF]
Nakamura S, Inoue R, Narimatsu H.
europepmc +1 more source

