Results 111 to 120 of about 14,679 (257)

TNF Pathway‐Mediated Tolerogenic T‐Cell Trajectory Driven by Allergen Immunotherapy

open access: yesAllergy, EarlyView.
The study shows that AIT re‐establishes local immune equilibrium by restoring Th17/Treg balance, while circulating Th17 cells remain functionally impaired. The transition from pro‐inflammatory Th17 to regulatory T cell states during AIT identifies Tr17 cells as an intermediate cell population.
Helen S. Charles   +20 more
wiley   +1 more source

Pushing the Limit for Marginal Grafts in the Era of Machine Perfusion: A Tale of HOPE From a Leading Italian Institution

open access: yesArtificial Organs, EarlyView.
HOPE has improved outcomes in ECD liver transplantation and allowed the safe utilization of increasingly marginal grafts with favorable results. ABSTRACT Background The advent of machine perfusion (MP) has significantly improved post‐liver transplantation (post‐LT) outcomes, potentially enabling the use of increasingly marginal grafts and expanding the
Gerti Dajti   +16 more
wiley   +1 more source

In for a penny: An empirical study of earthquake experience and non‐pharmaceutical intervention effectiveness in the Marche region

open access: yesAnnals of Public and Cooperative Economics, EarlyView.
Abstract This study investigates whether prior exposure to natural disasters influenced individual compliance with non‐pharmaceutical interventions (NPIs), specifically lockdown measures, during the Corona Virus Infectious Disease 2019 (COVID‐19) pandemic. Focusing on the Marche region of Italy, which experienced a severe earthquake in 2016, we exploit
Vincenzo Alfano   +2 more
wiley   +1 more source

Age differences in endocannabinoid tone are ameliorated after recent cannabis use. [PDF]

open access: yesSci Rep
Morris AWJ   +6 more
europepmc   +1 more source

New biosensors and transgenic mice for multiplex cGMP imaging

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters   +6 more
wiley   +1 more source

Integrated humoral and inflammatory signatures predict outcomes in severe COVID-19: a 14-day longitudinal analysis. [PDF]

open access: yesClin Transl Immunology
Ibiapina HNS   +23 more
europepmc   +1 more source

Environmentally adjusted productivity growth and shadow prices for dairy farms

open access: yesCanadian Journal of Agricultural Economics/Revue canadienne d'agroeconomie, EarlyView.
Abstract We estimate the environmentally adjusted productivity growth and shadow price for Ontario dairy farms. We use an input‐oriented directional distance function and farm‐level data from 2000 to 2020. First, we find that while GHG emissions per cow increase with higher milk yields, emission intensity decreases as milk yield per cow increases.
Bibek Dahal   +2 more
wiley   +1 more source

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