Results 151 to 160 of about 2,112,303 (205)

A DRACH Observed/Expected Metric Reveals the Evolutionary Landscape of Epitranscriptomic Regulation Across Bilateria

Annals of the New York Academy of Sciences, Volume 1564, Issue 1, October 2026.
Epitranscriptomic marks are highly variable across life stages and tissues, complicating comparisons between species. Using m6A consensus motifs, we developed a genomic indicator reflecting transcript methylability, the DRACH o/e score, that we used to investigate epitranscriptomic features and associated functions across nine bilaterian species.
Natacha Clairet, Jérémy Le Luyer, Hélène Auger, Maximilian Haeussler, Guillaume Rivière   +4 more
wiley   +1 more source

Rocaglates and pateamines target the DEAD-box RNA helicase eIF4A from Schistosoma mansoni and demonstrate anti-schistosomal activity in vitro. [PDF]

Sci Rep
Welsch S, Magari F, Mokosch AS, Haeberlein S, Gerbig S, Spengler B, Grünweller A, Grevelding CG.   +7 more
europepmc   +1 more source

Protein purification, crystallization, and structure determination of human DEAD-box RNA helicase DDX21 in different unwinding states. [PDF]

STAR Protoc, 2022
Chen Z, Huang J, Li J.
europepmc   +1 more source

ASXL1 in proinflammatory macrophages attenuates inflammatory activation and macrophage‐mediated renal tubular epithelial cell damage in acute kidney injury

Physiological Reports, Volume 14, Issue 19, October 2026.
ASXL1 in inflammatory macrophages attenuates renal tubular cell damage through coordinated histone modification of H3K27me3 and H3K4me3 in acute kidney injury. Abstract Macrophages are major contributors to inflammatory responses in acute kidney injury (AKI) and rapidly alter their gene expression through epigenetic regulation.
Yoshiyasu Ogura, Takehito Sugasawa, Masaomi Nangaku, Imari Mimura   +3 more
wiley   +1 more source

Structural basis for the activation of the DEAD-box RNA helicase DbpA by the nascent ribosome. [PDF]

Proc Natl Acad Sci U S A, 2021
Wurm JP, Glowacz KA, Sprangers R.
europepmc   +1 more source

Dual roles of DEAD-box RNA helicase Brr2 in genome stability regulation. [PDF]

Nat Commun
Chen X, You J, Ma Q, Lin J, Ji Y, Li S, Song Z, Su R, Shan G, Huang C.   +9 more
europepmc   +1 more source

Contribution of DEAD-Box RNA Helicase 21 to the Nucleolar Localization of Porcine Circovirus Type 4 Capsid Protein. [PDF]

Front Microbiol, 2022
Zhou J, Wang Y, Qiu Y, Wang Y, Yang X, Liu C, Shi Y, Feng X, Hou L, Liu J.   +9 more
europepmc   +1 more source

The DEAD-box RNA helicase eIF4A is a crucial factor for stem-cell activity and reproduction of the parasite <i>Schistosoma mansoni</i>. [PDF]

Front Cell Infect Microbiol
Welsch S, Puckelwaldt O, Ajmera S, Magari F, Haeberlein S, Grünweller A, Grevelding CG.   +6 more
europepmc   +1 more source

Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence. [PDF]

J Exp Clin Cancer Res, 2023
Li F, Ling X, Chakraborty S, Fountzilas C, Wang J, Jamroze A, Liu X, Kalinski P, Tang DG.   +8 more
europepmc   +1 more source

Regulatory role of the N-terminal intrinsically disordered region of the DEAD-box RNA helicase DDX3X in selective RNA recognition. [PDF]

Nat Commun
Toyama Y, Takeuchi K, Shimada I.
europepmc   +1 more source