Results 151 to 160 of about 32,587 (229)

DDX17 and viral infection

Virulence
DDX17 (DEAD-box RNA helicase 17) is an essential RNA helicase and regulatory ATPase in host cells, extensively involved in various cellular processes during viral infections, such as RNA splicing, transcriptional regulation, and post-transcriptional ...
Yuting Cheng, Ruohan Wang, Anping Wang, Zhi Wu, Wenfeng Jia, Huipeng Lu, Qingguo Wu, Shanyuan Zhu   +7 more
doaj   +1 more source

eIF4G stimulates the activity of the DEAD box protein eIF4A by a conformational guidance mechanism [PDF]

, 2017
The activity of eIF4A, a key player in translation initiation, is regulated by other translation factors through currently unknown mechanisms. Here, we provide the necessary framework to understand the mechanism of eIF4A's regulation by eIF4G.
Gubaev, Airat, Hilbert, Manuel, Kebbel, Fabian, Klostermeier, Dagmar   +3 more
core  

Characterisation of the DEAD Box RNA-Helicase Dbp10

, 2023
Ribosomen sind Ribonukleinkomplexe, welche die Translation der mRNA katalysieren und somit einer der wichtigsten Organellen in der Zelle. Sie bestehen aus einer großen Untereinheit (60S in Eukaryoten, 50S in Prokaryoten) und einer kleinen Untereinheit(40S in Eukaryoten, 30S in Prokaryoten) sowie ribosomaler RNA (18S; 5S; 5,8S; 25S) und ribosomalen ...
openaire  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio
Endothelial‐to‐mesenchymal transition (EndoMT), a widely recognized biological process leading to abnormal endothelial function, has been implicated in various cardiovascular pathologies.
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
doaj   +1 more source

Interplay between bacterial 5'-NAD-RNA decapping hydrolase NudC and DEAD-box RNA helicase CsdA in stress responses. [PDF]

mSystems, 2023
Mickutė M, Krasauskas R, Kvederavičiūtė K, Tupikaitė G, Osipenko A, Kaupinis A, Jazdauskaitė M, Mineikaitė R, Valius M, Masevičius V, Vilkaitis G.   +10 more
europepmc   +1 more source

Interaction of Teleost Fish TRPV4 with DEAD Box RNA Helicase 1 Regulates Iridovirus Replication. [PDF]

J Virol, 2023
Luo Z, Zhan Z, Qin X, Pan W, Liang M, Li C, Weng S, He J, Guo C.   +8 more
europepmc   +1 more source

Mutational analysis of the functional motifs of the DEAD-box RNA helicase Me31B/DDX6 in Drosophila germline development. [PDF]

FEBS Lett, 2023
Kara E, McCambridge A, Proffer M, Dilts C, Pumnea B, Eshak J, Smith KA, Fielder I, Doyle DA, Ortega BM, Mukatash Y, Malik N, Mohammed AR, Govani D, Niepielko MG, Gao M.   +15 more
europepmc   +1 more source

DEAD box RNA helicases are pervasive protein kinase interactors and activators

Genome Research
DEAD box (DDX) RNA helicases are a large family of ATPases, many of which have unknown functions. There is emerging evidence that besides their role in RNA biology, DDX proteins may stimulate protein kinases. To investigate if protein kinase–DDX interaction is a more widespread phenomenon, we conducted three orthogonal large-scale screens, including ...
Alexander Hirth, Edoardo Fatti, Eugen Netz, Sergio P. Acebron, Dimitris Papageorgiou, Andrea Švorinić, Cristina-Maria Cruciat, Emil Karaulanov, Alexandr Gopanenko, Tianheng Zhu, Irmgard Sinning, Jeroen Krijgsveld, Oliver Kohlbacher, Christof Niehrs   +13 more
openaire   +2 more sources

The DEAD-box RNA helicase, DDX60, Suppresses immunotherapy and promotes malignant progression of pancreatic cancer. [PDF]

Biochem Biophys Rep, 2023
Lai T, Su X, Chen E, Tao Y, Zhang S, Wang L, Mao Y, Hu H.   +7 more
europepmc   +1 more source

The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA viruses. [PDF]

EMBO Rep, 2022
Bonaventure B, Rebendenne A, Chaves Valadão AL, Arnaud-Arnould M, Gracias S, Garcia de Gracia F, McKellar J, Labaronne E, Tauziet M, Vivet-Boudou V, Bernard E, Briant L, Gros N, Djilli W, Courgnaud V, Parrinello H, Rialle S, Blaise M, Lacroix L, Lavigne M, Paillart JC, Ricci EP, Schulz R, Jouvenet N, Moncorgé O, Goujon C.   +25 more
europepmc   +1 more source