Results 131 to 140 of about 42,956 (259)

Al-Ansab and the Dead Sea: Mid-MIS 3 archaeology and environment of the early Ahmarian population of the Levantine corridor. [PDF]

PLoS One, 2020
Richter J, Litt T, Lehmkuhl F, Hense A, Hauck TC, Leder DF, Miebach A, Parow-Souchon H, Sauer F, Schoenenberg J, Al-Nahar M, Hussain ST.   +11 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Early Neutrophil Activation in Psoriatic Skin at Relapse Following Dead Sea Climatotherapy. [PDF]

Exp Dermatol
Emmanuel T, Ben Abdallah H, Baez E, Rather IM, Steiniche T, Bregnhøj A, Iversen L, Johansen C.   +7 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Resolving the slip-rate inconsistency of the northern Dead Sea fault. [PDF]

Sci Adv
Li X, Jónsson S, Liu S, Ma Z, Castro-Perdomo N, Cesca S, Masson F, Klinger Y.   +7 more
europepmc   +1 more source

Neotectonics of the Sea of Galilee (northeast Israel): implication for geodynamics and seismicity along the Dead Sea Fault system. [PDF]

Sci Rep, 2020
Gasperini L, Lazar M, Mazzini A, Lupi M, Haddad A, Hensen C, Schmidt M, Caracausi A, Ligi M, Polonia A.   +9 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Retraction Note: A Tunguska sized airburst destroyed Tall el-Hammam a Middle Bronze Age city in the Jordan Valley near the Dead Sea. [PDF]

Sci Rep
Bunch TE, LeCompte MA, Adedeji AV, Wittke JH, Burleigh TD, Hermes RE, Mooney C, Batchelor D, Wolbach WS, Kathan J, Kletetschka G, Patterson MCL, Swindel EC, Witwer T, Howard GA, Mitra S, Moore CR, Langworthy K, Kennett JP, West A, Silvia PJ.   +20 more
europepmc   +1 more source

A Tunguska sized airburst destroyed Tall el-Hammam a Middle Bronze Age city in the Jordan Valley near the Dead Sea.

Sci Rep, 2021
Bunch TE, LeCompte MA, Adedeji AV, Wittke JH, Burleigh TD, Hermes RE, Mooney C, Batchelor D, Wolbach WS, Kathan J, Kletetschka G, Patterson MCL, Swindel EC, Witwer T, Howard GA, Mitra S, Moore CR, Langworthy K, Kennett JP, West A, Silvia PJ.   +20 more
europepmc   +1 more source