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Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah +4 more
wiley +1 more source
Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen +24 more
wiley +1 more source
Dead space is that part of the tidal volume that does not participate in gas exchange. Although the concept of pulmonary dead space was introduced more than a hundred years ago, current knowledge and technical advances have only recently lead to the adoption of dead space measurement as a potentially useful bedside clinical ...
Lluís Blanch, U Lucangelo
exaly +6 more sources
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Characteristics of the washout dead space
Respiration Physiology, 1979The dead space volume was reproducibly measured in normal and diseased lungs by analysis of an inert gas washout. This washout dead space was appreciably larger than that measured by the Fowler technique. In the patients, the washout dead space (VD(0)) formed 72% of the physiological dead space volume, while the Fowler (VD(F)) method accounted for only
C J Martin, C J Martin
exaly +3 more sources
Pulmonary Dead Space and Survival
New England Journal of Medicine, 2002info:eu-repo/semantics ...
Feihl, François +2 more
openaire +3 more sources
Corrections of Enghoff's dead space formula for shunt effects still overestimate Bohr's dead space
Dead space ratio is determined using Enghoffs modification (VDB-E/V-T) of Bohr's formula (V-DBohr/V-T) in which arterial is used as a surrogate of alveolar PCO2. In presence of intrapulmonary shunt Enghoffs approach overestimates dead space.
João Batista Borges +2 more
exaly +2 more sources
Measurements of the dead space volume
Journal of Applied Physiology, 1979The “anatomical” dead space is commonly measured by sampling an inert gas (N2) and volume in the exhalation following a large breath of oxygen (VD(F)). It may also be measured from an inert gas washout (VD(O)) that describes both volume and the delivery of VD(O) throughout the expiration.
C J, Martin, S, Das, A C, Young
openaire +2 more sources
Respiration, 2009
The determination of dead space of any kind is rarely done because it is of more interest to determine blood gases and pH which will be altered as a result of the increase in the functional dead space (anatomic and physiologic). The most frequent cause of increased dead space is an imbalance between ventilation and perfusion, and this alteration is ...
openaire +2 more sources
The determination of dead space of any kind is rarely done because it is of more interest to determine blood gases and pH which will be altered as a result of the increase in the functional dead space (anatomic and physiologic). The most frequent cause of increased dead space is an imbalance between ventilation and perfusion, and this alteration is ...
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Determination of the alveolar dead space
Bulletin of Experimental Biology and Medicine, 1979The author suggests a method of finding the alveolar dead space (AIDS), i.e. the part of the functional dead space (FDS) which presents the greatest difficulties for determination. A1DS determination is based on the difference in the CO2 concentration in the venous blood flowing to the lungs for oxygenation under conditions of respiration at rest, and ...
openaire +2 more sources

