From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The effect of a pediatric heat and moisture exchanger on dead space in healthy pediatric anesthesia [PDF]
BackgroundHeat and moisture exchangers (HME) are often used to maintain humidity of breathing circuits during anesthesia. It is also known to increase dead space ventilation in respiratory distress syndromes.
Min A Kwon
doaj +1 more source
Spatial Evaluation Based on The Volume of Space Utilization in Low-Income Public Housing
The need for storage space at home has increased following the Covid-19 pandemic, yet in the design process of residential space, storing space is often neglected.
Nurrul Helen, Evawani Ellisa
doaj +1 more source
TRACHEAL DEAD SPACE IN THE RESPIRATION OF BIRDS [PDF]
Some of the most compelling evidence for organic evolution has been provided in cases of evolutionary convergence. The examples of convergence most commonly cited are qualitative morphological descriptions. However, quantitative allometric analysis can direct our attention to the possibility that a given problem may have a very limited number of ...
David S, Hinds, William A, Calder
openaire +2 more sources
FitzwilliamMuseum/fitz-book-of-the-dead: Book of the Dead: Production release
What's Changed Bump addressable from 2.7.0 to 2.8.0 by @dependabot in https://github.com/FitzwilliamMuseum/fitz-book-of-the-dead/pull/1 Bump nokogiri from 1.11.7 to 1.12.5 by @dependabot in https://github.com/FitzwilliamMuseum/fitz-book-of-the-dead/pull/
Daniel Pett
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
EVALUATION OF VENTILATION-PERFUSION RATIO IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Objective: To study ventilation-perfusion ratio (VPR) in patients with chronic obstructive pulmonary disease (COPD) using method of volumetric capnography.
T.A. MIROSHKINA +2 more
doaj +1 more source
Studies of the Respiratory Dead Space Ⅰ: The respiratory dead space in Japanese healthy sudjects [PDF]
The respiratory dead space in Japanese healthy 45 males and 30 females were estimated by Bohr formula from the tidal volume and the CO(2) percenttage of alveolar and expired air in sitting posture during rest.
Moriya, Takeo
core
Dead space in acute respiratory distress syndrome
Dead space is the portion of each tidal volume that does not take part in gas exchange and represents a good global index of the efficiency of the lung function.
Ferluga, Massimo +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

