Results 71 to 80 of about 4,433,033 (299)

Physical and Physiological Mechanisms of Emergent Hydrodynamic Pressure in High-Flow Nasal Cannula Therapy

Advances in Respiratory Medicine
High-flow nasal cannula (HFNC) therapy is frequently described as a positive pressure modality, yet this classification lacks mechanistic support. This critical narrative review integrates experimental, computational, and clinical evidence to examine the
Jose Luis Estela-Zape
doaj   +1 more source

Associação entre índice de ventilação e tempo de ventilação mecânica em lactentes com bronquiolite viral aguda Association between ventilation index and time on mechanical ventilation in infants with acute viral bronchiolitis

Jornal de Pediatria, 2005
OBJETIVO: Avaliar a associação entre tempo de ventilação mecânica e variáveis antropométricas, clínicas e de função pulmonar, precocemente, em lactentes com insuficiência respiratória por bronquiolite viral aguda em ventilação mecânica invasiva, e a ...
Armando A. Almeida-Júnior, Marcos T. N. da Silva, Celize C.B. Almeida, Andréa D. N. Jácomo, Breno M. Nery, José D. Ribeiro   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

A Bilobed Lipoma Presenting in the Post-Excision Space of the Radial Head 5 Years after Radial Head Excision: A Case Report

Journal of Orthopaedic Case Reports
Introduction: Lipoma is the commonest benign soft-tissue tumor, but its occurrence within a surgically created dead space is exceedingly rare. Radial head excision leaves a void in the lateral compartment of the elbow that is ordinarily obliterated by ...
V S Subramaniyan, Naveen Gowda, Deepender Suhag, Charan Kumar, Syed Wahaj   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Prevention and Management of Postoperative Seroma in Patients with Breast Cancer: A Narrative Review

Journal of Investigative Surgery
Introduction Postoperative seroma remains a frequent complication following breast cancer surgery in both sexes. Despite continuous surgical advancements, its incidence widely ranges from 3% to 85%, significantly affecting the postoperative course ...
Anastasiia Samusieva, Vitalii Zaichuk, Prokip Gordiichuk   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Anatomic Dead Space Cannot Be Predicted by Body Weight [PDF]

, 2007
Anatomic, airway, or tracheal, dead space is the part of the tidal volume that does not participate in gas exchange. Knowledge of the size of the dead space is important for proper mechanical ventilation, especially if small tidal volumes are used ...
Orr, Joseph A., Brewer, Lara M.
core   +1 more source

A neglected problem in the utilization of free anterolateral thigh flap toward reconstructing complicated wounds of extremities: the obliteration of deep dead space

Journal of Orthopaedic Surgery and Research, 2020
Background Deep dead space may be thought as an independent risk factor of the poor infection control after flap reconstruction in complex limb wounds. But it can be easily neglected.
Gao-hong Ren, Da-yong Xiang, Xiao-hu Wu, Yun-biao Chen, Runguang Li   +4 more
doaj   +1 more source

Unanesthetized dogs with increased respiratory dead space

, 1960
A method is described for maintaining a permanent tracheostomy in dogs. This animal preparation has been used to study the effects of artificially increased respiratory dead space.
Thomas B. Barnett, Richard M. Peters
core   +1 more source