Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
Phylogenetic analyses and morphological studies reveal two new species of <i>Biscogniauxia</i> (<i>Xylariales</i>, <i>Ascomycota</i>) from Hainan Tropical Rainforest National Park, China. [PDF]
Ma SY +5 more
europepmc +1 more source
Defect-Mask2Former: An Improved Semantic Segmentation Model for Precise Small-Sized Defect Detection on Large-Sized Timbers. [PDF]
Qin M, Li H, Huang Y, Tong X, Liang Z.
europepmc +1 more source
Community Structure and Diversity of Scolytinae in Two Mangrove Ecosystems of Western Mexico. [PDF]
Figueroa-Vázquez J +7 more
europepmc +1 more source
Three novel aquatic species of <i>Distoseptispora</i> (Distoseptisporaceae, Distoseptisporales) from the Philippines, with a new geographic record for <i>D. septata</i>. [PDF]
Bagacay JFE +7 more
europepmc +1 more source
Anticancer Properties of Selected Wood-Inhabiting Fungi. [PDF]
Roszczenko P +7 more
europepmc +1 more source
Mechanisms of <i>Poria cocos</i> Wood Colonization: Host Nutrient Depletion and Secondary Metabolite Defense. [PDF]
Meng X, Han M, Gu X, Zou L.
europepmc +1 more source
Dead wood is essential for biodiversity in forests and is therefore often surveyed in conservation inventories. Usually only coarse downed trees (logs) and standing dead trees (snags) are surveyed, but dead wood also occurs on living trees, in stumps ...
Björn Nordén +2 more
exaly +2 more sources

