Results 91 to 100 of about 5,370,379 (308)
A fishbowl discussion at the AGMB conference 2024 addressed the question of whether and how the German DEAL with three major publishers influences publication behavior at medical institutions. Participants’ contributions showed a strong bundling of costs
Labriga, Petra
doaj +1 more source
Time for play – An exploratory analysis of the changing consumption contexts of digital games [PDF]
This study posits that Internet technologies are relaxing the coupling constraints required for the consumption of digital games, resulting in entirely different modes of consumption than has been the norm for the past thirty years.
Deal, David
core +1 more source
Sweatfree Communities Statement on New Trade Deal [PDF]
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
International Labor Rights Forum +1 more
core +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
AGMB 2024: Den Wandel steuern – Medizininformation effizient.digital.innovativ
This issue of GMS Medizin – Bibliothek – Information takes up the topics of the 2024 annual conference of the German Medical Libraries Association (AGMB) in Mainz.
Reimann, Iris
doaj +1 more source
Fingering convection induced by atomic diffusion in stars: 3D numerical computations and applications to stellar models [PDF]
Iron-rich layers are known to form in the stellar subsurface through a combination of gravitational settling and radiative levitation. Their presence, nature and detailed structure can affect the excitation process of various stellar pulsation modes, and
Deal, Morgan +3 more
core +3 more sources
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Studies related to the development of the Viking 1975 labeled release experiment [PDF]
The labeled release life detection experiment on the Viking 1975 Mars mission is based on the concept that microorganisms will metabolize radioactive organic substrates in a nutrient medium and release radioactive carbon dioxide.
Deal, P. H., Devincenzi, D. L.
core +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source

