Results 101 to 110 of about 5,374,884 (305)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Studies related to the development of the Viking 1975 labeled release experiment [PDF]

open access: yes
The labeled release life detection experiment on the Viking 1975 Mars mission is based on the concept that microorganisms will metabolize radioactive organic substrates in a nutrient medium and release radioactive carbon dioxide.
Deal, P. H., Devincenzi, D. L.
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Actual Problems of Civil Law Deals Signing in Internet

open access: yesVestnik Omskoj Ûridičeskoj Akademii, 2013
The article deals with the problems connected with making deals in Internet. Here is analyzed the legal regulation of electronic transactions. The special attention is paid to the most characteristic peculiarities of making elec- tronic transactions such
Makhinya E. A.
doaj   +2 more sources

Die Folgen von DEAL für medizinische Bibliotheken: Bericht aus der Fishbowl-Diskussion auf der AGMB-Tagung 2024 in Mainz

open access: yesGMS Medizin – Bibliothek – Information
A fishbowl discussion at the AGMB conference 2024 addressed the question of whether and how the German DEAL with three major publishers influences publication behavior at medical institutions. Participants’ contributions showed a strong bundling of costs
Labriga, Petra
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

AGMB 2024: Den Wandel steuern – Medizininformation effizient.digital.innovativ

open access: yesGMS Medizin – Bibliothek – Information
This issue of GMS Medizin – Bibliothek – Information takes up the topics of the 2024 annual conference of the German Medical Libraries Association (AGMB) in Mainz.
Reimann, Iris
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy