Results 41 to 50 of about 5,370,379 (308)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
China Journal of Accounting Studies, 2023 This study investigates the competitive strategies of the international Big 4 audit firms when faced with regional competition from the local Big 6 audit firms.
Qingquan Xin, Yu Liu, Yiheng Tang
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An Exploratory Exercise in Taguchi Analysis of Design Parameters: Application to a Shuttle-to-space Station Automated Approach Control System [PDF]
, 1991 The chief goals of the summer project have been twofold - first, for my host group and myself to learn as much of the working details of Taguchi analysis as possible in the time allotted, and, secondly, to apply the methodology to a design problem with ...
Deal, Don E.
core +1 more source
Risky Choice and Type-Uncertainty in 'Deal or No Deal?' [PDF]
, 2007 This paper uses data from the popular television game-show, "Deal or No Deal?", to analyse the way individuals make choices under risk. In a unique approach to the problem, I present a formal game-theoretical model of the show in which both the ...
Gee, Christopher
core +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
BIM competencies for delivering waste-efficient building projects in a circular economy
Developments in the Built Environment, 2020 Competency measures are increasingly becoming effective ways for construction organizations to measure their ability to deliver waste-efficient projects.
Sikiru Abiodun Ganiyu +5 more
doaj +1 more source
Deep learning-based multi-target regression for traffic-related air pollution forecasting
Machine Learning with Applications, 2023 Traffic-related air pollution (TRAP) remains one of the main contributors to urban pollution and its impact on climate change cannot be overemphasised.
Taofeek Dolapo Akinosho +5 more
doaj +1 more source
Anatomy of a Preservation Deal [PDF]
, 2016 In 2013, the owner, the Melville Charitable Trust, selected Preservation of Affordable Housing, Inc. (POAH), to leverage investment for capital improvements while ensuring continued housing affordability and increasing resident services. POAH was able to
Mark Treskon, Sara McTarnaghan
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source