Results 61 to 70 of about 1,150 (206)

Preservation of Extracellular Vesicle Integrity and Cargo Using Spiral Microfluidic Chip‐Based Separation

open access: yesAdvanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.
A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee   +5 more
wiley   +1 more source

Enhancement of Fluid Mixing with U-Shaped Channels on a Rotating Disc

open access: yesMicromachines, 2020
In this study, centrifugal microfluidics with a simple geometry of U-shaped structure was designed, fabricated and analyzed to attain rapid and efficient fluid mixing.
Chi-Wei Hsu, Po-Tin Shih, Jerry M. Chen
doaj   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

open access: yesAdvanced Science, Volume 13, Issue 30, 28 May 2026.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie   +7 more
wiley   +1 more source

Semi-Empirical Estimation of Dean Flow Velocity in Curved Microchannels

open access: yes, 2017
Curved and spiral microfluidic channels are widely used in particle and cell sorting applications. However, the average Dean velocity of secondary vortices which is an important design parameter in these devices cannot be estimated precisely with the ...
Pouya Rezai, Pouriya Bayat
core   +1 more source

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

open access: yesBiotechnology Progress, Volume 42, Issue 3, May/June 2026.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg   +8 more
wiley   +1 more source

Numerical study of Dean vortices in developing Newtonian and viscoelastic flows through a curved duct of square cross-section [PDF]

open access: yes, 2009
International audienceThis study is devoted to the three-dimensional numerical simulation of developing secondary flows of Newtonian and viscoelastic fluids through a curved duct of square cross-section.
Mohammed Boutabaa   +7 more
core   +1 more source

Voltage-Dependent Optimization of Split-Flow Channels in High-Temperature PEM Fuel Cells: Balancing Ohmic and Concentration Polarization

open access: yesEnergies
High-temperature proton exchange membrane fuel cells (HT-PEMFCs) coupled with methanol reforming hold promise for distributed energy systems, yet channel hydrodynamics and geometry optimization remain underexplored.
Chenliang Guo   +7 more
doaj   +1 more source

Mixing Enhancement in Serpentine Micromixers with a Non-Rectangular Cross-Section

open access: yesMicromachines, 2018
In this numerical study, a new type of serpentine micromixer involving mixing units with a non-rectangular cross-section is investigated. Similar to other serpentine/spiral shaped micromixers, the design exploits the formation of transversal vortices ...
Joshua Clark   +2 more
doaj   +1 more source

3D‐Printed Coil Immobilized Enzyme Reactors for Laccase Biocatalysis in Single‐ and Two‐Phase Flow

open access: yesChemie Ingenieur Technik, Volume 98, Issue 5, Page 212-223, May 2026.
Development of 3D‐printed immobilized enzyme reactors functionalized with laccase for continuous‐flow biocatalysis. Surface coupling and reactor design enhanced stability and mass transfer, enabling efficient and reusable biocatalytic processes.
Alina J. Tauriainen   +4 more
wiley   +1 more source

Coupled Fluid–Structure–Acoustic Analysis of Flow‐Induced Noise Control Using an Elastic Baffle in a Micro Channel

open access: yesEnergy Science &Engineering, Volume 14, Issue 5, Page 2571-2582, May 2026.
This research explores how fluid flow, structural movement, and sound interact in an elastic baffle system. Using a numerical approach based on the finite element method, the study analyzes how noise and vibrations change with different baffle configurations. The findings reveal that shortening the baffle by half reduces noise transmission by 9%, while
Tohid Adibi   +5 more
wiley   +1 more source

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