Results 91 to 100 of about 351,654 (205)

2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death.

Circulation, 2018
S. Al‐Khatib, W. Stevenson, M. Ackerman, William J. Bryant, D. Callans, A. Curtis, B. Deal, T. Dickfeld, M. Field, G. Fonarow, A. Gillis, C. Granger, S. Hammill, M. Hlatky, J. Joglar, G. Kay, D. Matlock, R. Myerburg, R. Page   +18 more
semanticscholar   +1 more source

Hypoxia‐Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β‐Catenin Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu, Jing‐Wen Hou, Zhong‐Ying Lv, Ming‐Hui Sun, Xiao‐Yang Zhang, Lei Zhang, Mei Wang   +6 more
wiley   +1 more source

[2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death].

Kardiologia polska, 2015
S. Priori, Carina Blomström-Lundqvist, Andrea Mazzanti, Nico Blom, Martin Borggrefe, J. Camm, P. M. Elliott, Donna Fitzsimons, Robert Hatala, G. Hindricks, P. Kirchhof, K. Kjeldsen, K. Kuck, A. Hernández–Madrid, Nikolaos Nikolaou, T. M. Norekvål, Christian Spaulding, D. J. van Veldhuisen   +17 more
semanticscholar   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

Movement Disorders Clinical Practice, EarlyView.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori, Yohei Mukai, Noriko Nishikawa, Kazuko Hasegawa, Masahiko Tomiyama, Yasuyoshi Kimura, Yoshio Tsuboi, Ryosuke Takahashi, Ryota Nakamura, Yuishin Izumi, Hirohisa Watanabe, Morinobu Seki, Kenji Sekiguchi, Shohei Tateishi, Yusaku Matsushita, Yusaku Nakamura   +15 more
wiley   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Cardiac resynchronization therapy and pulmonary artery banding in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block

Pediatric Investigation, EarlyView.
The combination of cardiac resynchronization therapy and pulmonary artery banding was associated with substantial improvement in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block. Most patients exhibited marked improvement in clinical status and ventricular function, along with a reduction in QRS ...
Min Zeng, Fan Yang, Quanlin Li, Kai Ma, Zheng Dou, Kunjing Pang, Xinjie Lin, Shoujun Li, Xu Wang   +8 more
wiley   +1 more source

Epidemiology of Sudden Cardiac Death: Global and Regional Perspectives.

Heart, Lung and Circulation, 2019
Christopher X. Wong, A. Brown, D. Lau, S. Chugh, C. Albert, J. Kalman, P. Sanders   +6 more
semanticscholar   +1 more source

Multifrequency Multiparameter Magnetic Resonance Elastography Applied to an In Vivo Porcine Model for Assessing Portal Hypertension

Portal Hypertension &Cirrhosis, EarlyView.
Portal hypertension, a critical complication in chronic liver disease, has long relied on invasive hepatic venous pressure gradient measurement for definitive diagnosis. This study establishes that multifrequency three‐dimensional magnetic resonance elastography (3D‐MRE) can noninvasively quantify portal pressure, with splenic stiffness and loss ...
Bai Du, Xiaolong Qi, Yujia Ma, Chen Pan, Qijun Wu, Meng Niu, Yu Shi   +6 more
wiley   +1 more source

Impact of Lipid Profile Alterations on the Right Heart Function and Prognosis in Pre‐Capillary Pulmonary Hypertension Patients: A Prospective Cohort Study

Respirology, EarlyView.
This study found that reduced HDL‐C correlates with impaired RV systolic function and RA strain, highlighting a mechanistic link between lipid abnormalities and right heart remodelling. Additionally, decreased HDL‐C and LDL‐C were identified as independent mortality predictors in precPH patients. Integrating lipid parameters into ESC and ESC‐CMR models
Jiajun Guo, Ji Zhao, Jiaqi Wang, Yangjie Li, Juan He, Chen Chen, Xuhan Liu, Lidan Yin, Shoufang Pu, Bi Wen, Min Luo, Yuanwei Xu, Ke Wan, Yuchi Han, Yucheng Chen   +14 more
wiley   +1 more source