Results 191 to 200 of about 262,262 (298)

Extracellular vesicle microRNAs are biomarkers of focal epilepsy but not epilepsy‐related respiratory dysfunction

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the diagnostic value of a set of preselected candidate microRNAs (miRNAs) extracted from plasma‐based extracellular vesicles (EVs) to identify patients with seizure‐related respiratory dysfunction. Methods A two‐step design was applied.
Sylvain Rheims, Hayet Kouchi, Florence Busato, Stanislas Lagarde, David Derbala, Sébastien Boulogne, Mathilde Leclercq, Jessica Chenais, Sandrine Bouvard, Fabrice Bartolomei, Laurent Bezin, Jorg Tost   +11 more
wiley   +1 more source

Left ventricular ejection fraction and myocardial fibrosis in sudden cardiac death. [PDF]

Europace
Silvola H, Holmström L, Pakanen L, King I, Eskuri A, Tikkanen J, Perkiömäki J, Huikuri H, Junttila J.   +8 more
europepmc   +1 more source

Artificial intelligence‐driven closed‐loop devices in sudden unexpected death in epilepsy prediction and prevention: Insights from persons with epilepsy and caregivers

Epilepsia, EarlyView.
Abstract Objective The absence of strategies for predicting and preventing sudden unexpected death in epilepsy (SUDEP) is intertwined with the lack of studies measuring users' attitudes toward potential innovative interventions. The NEUROSENSE Project (http://www.neurosense‐project.eu) aims to evaluate novel SUDEP‐predictive neuroendocrine biomarkers ...
João Ferreira, Miguel França, Mariana Cardoso Regalo, Mariana Rei, Ricardo Peixoto, José Ángel Aibar, Torie Robinson, Ricardo Matias, Fabrice Duprat, Massimo Mantegazza, Onur Parlak, Philippe Ryvlin, Sándor Beniczky, Lígia Lopes, Emilio Perucca, João Claro, Carlos Conde   +16 more
wiley   +1 more source

Identification of Two Rare Variants in Iranian Families With Familial Sudden Cardiac Death. [PDF]

Int J Genomics
Tahmasebivand M, Mehvari S, Ghodratpour F, Khoram Khorshid H, Malekzadeh R, Najafipour R, Riazalhosseini Y, Lathrop M, Najmabadi H, Kahrizi K.   +9 more
europepmc   +1 more source

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun, Rachel Spera, John M. Williamson, Suchitra Joshi, Bhavya Guduru, Harini Ganabady, Jaideep Kapur   +6 more
wiley   +1 more source

Trends in Sudden Death Among Schizophrenia Inpatients. [PDF]

Medicina (Kaunas)
Popa AV, Ifteni PI, Petric PS, Țâbian D, Teodorescu A.   +4 more
europepmc   +1 more source

Bexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC)

Epilepsia, EarlyView.
Abstract Objective This randomized, double‐blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and efficacy of oral bexicaserin versus placebo for the treatment of seizures in adolescents and adults with developmental and epileptic encephalopathies (DEEs).
Dennis J. Dlugos, Ingrid E. Scheffer, Jacqueline A. French, David G. Vossler, Chad Orevillo, Shikha Polega, Randall Kaye, and the LP352‐201 Study Investigators, Kore Liow, Ena Zhu, Jennifer Waldron, Hayley Groubert, Alexis Anderson, Pavel Klein, Salman Hashmi, Shicong Ye, Anita Farhi, David Vossler, Dione M. Froman, Shannon L. Hoffman‐Huffaker, Ki Hyeong Lee, AnnaLyn Dallas, Amir Arain, Laura Beeler, Michael Macken, Irena Bellinski, Elizabeth Cunningham, James Renfroe, Shezsay Colbert, Robert Hogan, Patty Schaefer, Susan Shaw, Sheetal Desai, Ahmed Sadek, Haile Robertson, Kamil Detyniecki, Anabela Cieslicki, Ruben Kuzniecky, Sarah Goodman, Selim Benbadis, Marina Azevedo, Sami Aboumatar, Julie Biel, Nilika Singhal, Emerald Wan, Evan Fertig, Hannah Hart, Debopam Samanta, Sarah Hankins, Steven Wolf, Patricia Pena, Robert Nahouraii, M. J. Mari, David Burdette, Stephanie Mueller, Karen Keough, Victoria Henderson, Talitha Durgin, Terence O’Brien, Rafael Smith, Jack Germaine, Kate Riney, Lori Anthony, David Reutens, Kimberley Irwin, Michael Fahey, Melissa Batt, Stephanie Kaladis, Kasthoori Jeyachanthiran, Ingrid Scheffer, Rebecca Wharrie, Greesha Zacharia, Brittany Walsh, Heather Robinson, Sharon Ganter   +74 more
wiley   +1 more source

Layer-specific proteomic analysis of human hearts in patients with sudden cardiac death. [PDF]

PLoS One
Kakimoto Y, Guan X, Ueda A, Kimura Y, Akiyama T, Tanaka M, Ikeda H, Maeda K, Isozaki S.   +8 more
europepmc   +1 more source

Clinical outcomes following stereotactic MRI‐guided laser ablation in children with tuberous sclerosis complex and intractable epilepsy

Epilepsia, EarlyView.
Abstract Objective In children with tuberous sclerosis complex (TSC) and drug‐resistant epilepsy (DRE), magnetic resonance imaging–guided stereotactic laser ablation (SLA) therapy offers less‐invasive treatment compared to craniotomy and resection. Our study seeks to further expand on the long‐term outcomes in patients with TSC‐related DRE who have ...
Chelsey Ortman, Rohini Coorg, Irfan Ali, Dave Clarke, Gloria Diaz‐Medina, Kimberly Houck, Akshat Katyayan, Laura Masters, Deepankar Mohanty, Anuranjita Nayak, Michael Quach, Vijay M. Ravindra, James J. Riviello, Sonali Sen, Elaine Seto, Danielle Takacs, Cristina Trandafir, John T. Freiling, Karen Evankovich, Yingchao Yuan, Kalman A. Katlowitz, Daniel Curry, Howard L. Weiner, Anne Anderson   +23 more
wiley   +1 more source

Catecholaminergic polymorphic ventricular tachycardia in children-incidence and trends in detection, presentation and management. [PDF]

Arch Dis Child
Fitzgerald N, Lawley C, Morrish A, Tarca A, Marcondes L, Asakai H, Turner C, Skinner J.   +7 more
europepmc   +1 more source