Results 191 to 200 of about 337,480 (272)

Perioperative Mechanical Circulatory Support for Cardiac Assistance in Thoracic Surgery: A Scoping Review

open access: yesArtificial Organs, EarlyView.
High‐risk cardiac patients may benefit from timely temporary mechanical circulatory support (tMCS) implantation to provide perioperative hemodynamic stabilization and circulatory support, thus enabling them to undergo life‐saving thoracic surgery. CPB: cardiopulmonary bypass; IABP: intra‐aortic balloon pump; tMCS: temporary mechanical circulatory ...
Viviana Teresa Agosta   +4 more
wiley   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

open access: yes
The Journal of Dermatology, EarlyView.
Yoshihide Asano   +27 more
wiley   +1 more source

Impact of Frailty in Patients With Continuous‐Flow Left Ventricular Assist Device Therapy in End‐Stage Heart Failure: A Systematic Review and Meta‐Analysis

open access: yesArtificial Organs, EarlyView.
Frailty significantly impacts clinical outcomes in LVAD recipients. This systematic review and meta‐analysis reveal that frail patients experience higher long‐term mortality but comparable short‐term mortality, hospital stay, and complication rates to non‐frail patients.
Christos Costa   +15 more
wiley   +1 more source

Slow Codes are symptomatic of ethically and legally inappropriate CPR policies

open access: yesBioethics, Volume 39, Issue 4, Page 327-336, May 2025.
Abstract Although cardiopulmonary resuscitation (CPR) was initially used very selectively at the discretion of clinicians, the use of CPR rapidly expanded to the point that it was required to be performed on all patients having in‐hospital cardiac arrests, regardless of the underlying condition.
Stuart McLennan   +2 more
wiley   +1 more source

Potentiating microglial efferocytosis by MFG‐E8 improves survival and neurological outcome after successful cardiopulmonary resuscitation in mice

open access: yesBrain Pathology, EarlyView.
Schematic representation of the effects of rmMFG‐E8 on post‐CA/CPR brain injury. Ischemic/reperfusion injury caused by CA/RCA results in elevated apoptotic cell death in various cells and decreased apoptotic cell clearance by phagocytes, such as microglia.
Kunxue Zhang   +9 more
wiley   +1 more source

Late‐onset multiple system atrophy: Neuropathological features associated with slow disease progression

open access: yesBrain Pathology, EarlyView.
Late‐onset multiple system atrophy (LO‐MSA; onset ≥75 years) shows milder degeneration of the striatonigral and olivopontocerebellar systems and serotonergic neurons in the ventrolateral medulla than usual‐age‐onset MSA with a similar disease duration. LO‐MSA may therefore exhibit slower pathological progression.
Misato Ozawa   +13 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Rescue of loss‐of‐function long QT syndrome‐associated mutations in KV7.1/KCNE1 by the endocannabinoid N‐arachidonoyl‐L‐serine (ARA‐S)

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Congenital long QT syndrome (LQTS) involves genetic mutations affecting ion channels, leading to a prolonged QT interval and increased risk of potentially lethal ventricular arrhythmias. Mutations in the genes encoding KV7.1/KCNE1 are the most frequent, with channel loss‐of‐function contributing to LQTS.
Irene Hiniesto‐Iñigo   +11 more
wiley   +1 more source

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