Results 21 to 30 of about 5,535 (166)

Aborted sudden cardiac death due to ventricular fibrillation in a female patient with mitral valve prolapse

Cardiovascular Ultrasound, 2021
Background Mitral valve prolapse is the most frequent valvular defect associated with a wide range of electro-hemodynamic abnormalities, leading to heart failure, arrhythmias and sudden cardiac death. Mitral valve prolapse, first described from Barlow in
Sofien Ayed, Rainer Hoffmann
doaj   +1 more source

Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8

Advanced Science, EarlyView.
Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong, Zhen Guo, Yu‐Lan Ma, Ming‐Yu Wang, Hai‐Yang Ni, Pan Wang, Wen‐Jun Qiu, En‐Gui Wang, Zhou Li, Zheng Yang, Bo Shen, Qi‐Zhu Tang   +11 more
wiley   +1 more source

Appropriate time interval to update ambiguous genetic diagnosis in inherited arrhythmogenic syndromes

iScience
Summary: Genetic analysis identified the cause of the disease in inherited arrhythmogenic syndromes. A clinically actionable genetic diagnosis requires an accurate interpretation following the current guidelines. Practically half of the genetic diagnoses
Estefanía Martínez-Barrios, Andrea Greco, Sergi Cesar, Carles Díez-López, José Cruzalegui, Nuria Díez-Escuté, Patricia Cerralbo, Fredy Chipa, Irene Zschaeck, Simone Grassi, Antonio Oliva, Norma Balderrábano, Rocío Toro, Georgia Sarquella-Brugada, Oscar Campuzano   +14 more
doaj   +1 more source

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

Advanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang, Zhi‐Xue Song, Si‐Ming Bu, Yi‐Mei Liu, Qing Li, Wen‐Xia Zhang, Xu‐Rong Sun, Xin Zhang, Yu‐Xuan Xiao, Di Bo, Xu‐Bin Miao, Chao Liu, Xin‐Hua Zhang, Lei Zheng, Hong‐Ye Zhao, Bao‐Lian Zhang, Wen Jia, Kui Chi, Yu Liu, Yong‐Bo Zhao, Bin Zheng, Dong Ma, Jin‐Kun Wen   +22 more
wiley   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

Advanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo   +12 more
wiley   +1 more source

CURRENT ASPECTS OF THE CONCEPT, ETIOLOGY, PATHOGENESIS AND PREVENTION OF SUDDEN CARDIAC DEATH

Наука и инновации в медицине, 2017
Aim - to highlight current aspects of the concept, etiology, pathogenesis and prevention of sudden cardiac death. Discussion. Sudden cardiac death in a wide sense is known as non-violent death due to cardiac pathology, with the rapid development of ...
OV V Fatenkov, OA A Rubanenko, SS S Yashin, DB B Avezova   +3 more
doaj   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

Advanced Science, EarlyView.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

The Metabolic Syndrome and Risk of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundPrior studies have demonstrated a link between the metabolic syndrome and increased risk of cardiovascular mortality. Whether the metabolic syndrome is associated with sudden cardiac death is uncertain.
Paul L. Hess, Hussein R. Al‐Khalidi, Daniel J. Friedman, Hillary Mulder, Anna Kucharska‐Newton, Wayne R. Rosamond, Renato D. Lopes, Bernard J. Gersh, Daniel B. Mark, Lesley H. Curtis, Wendy S. Post, Ronald J. Prineas, Nona Sotoodehnia, Sana M. Al‐Khatib   +13 more
doaj   +1 more source

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

Advanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song, Yu Wei, Peng Jia, Shan He, Qian Wang, Manman Xu, Hongzhi Liu, Pengtao Bao, Shanyue Guan, Xiaozhong Qu   +9 more
wiley   +1 more source