Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy
Abstract Objective The NeuroPace responsive neurostimulation (RNS) System effectively treats focal drug‐resistant epilepsy (DRE) in adults but lacks pediatric regulatory approval. Despite effective off‐label pediatric use, systemic device‐trial challenges have impeded label expansion.
Mira C. Hasner +15 more
wiley +1 more source
Characteristics of Sudden Unexpected Infant Deaths - United States, 2020-2024. [PDF]
Lambert ABE +6 more
europepmc +1 more source
A Prospective Study of Sudden Cardiac Death among Children and Young Adults.
R. Bagnall +27 more
semanticscholar +1 more source
Localizing value of ecstatic phenomenon in epilepsy surgery: A systematic review
Abstract Objective A systematic review was conducted to synthesize current anatomo‐clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence‐based guidance for interpreting this ictal semiology during presurgical evaluation.
Mihai Dragos Maliia +2 more
wiley +1 more source
Artificial intelligence for adaptive neuromodulation in drug‐resistant epilepsy
Abstract Drug‐resistant epilepsy (DRE) affects nearly one third of people with epilepsy and is associated with substantial cognitive, psychiatric, and mortality burdens. For patients who are not candidates for resection or laser interstitial thermal therapy, neuromodulation therapies such as vagus nerve stimulation, deep brain stimulation, and ...
Amir Hossein Daraie +10 more
wiley +1 more source
Perils and progress in epilepsy surgery utilization: Twenty‐five years later
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley +1 more source
Sudden Cardiac Death as the First Manifestation of Arrhythmogenic Right Ventricular Cardiomyopathy in a Young Female Athlete: Postmortem Morphologic Diagnosis. [PDF]
Deronjic J +7 more
europepmc +1 more source
Epileptic arousals: A neglected clinical entity
Abstract Objective Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in scalp electroencephalography (EEG) complicate differentiation from physiological arousals (PAs). This study characterizes EAs
Lea Fisel +8 more
wiley +1 more source
Sorcery and Sudden Death [PDF]
openaire +2 more sources
Climate‐related exposures and seizures in children: A systematic review
Abstract Objective Climate‐related exposures, including air pollution, temperature extremes, humidity, and atmospheric conditions, are increasingly recognized as potential seizure triggers. As climate change intensifies, understanding the environmental contributors to pediatric seizure risk has important implications for anticipatory guidance and ...
Caroline Sarpy +5 more
wiley +1 more source

