Results 241 to 250 of about 299,978 (312)

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11‐year longitudinal study and proposed diagnostic red flags

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi   +6 more
wiley   +1 more source

Effectiveness and safety of implantable vagus nerve stimulation in people with primary generalized tonic–clonic seizures

open access: yesEpilepsia Open, EarlyView.
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston   +6 more
wiley   +1 more source

Writing with a broken heart: Literature and the many faces of grief. [PDF]

open access: yesPalliat Support Care
Antuña-Zarzuelo E   +2 more
europepmc   +1 more source

Real‐world effectiveness of cenobamate in drug‐resistant and ultra‐refractory epilepsy: A multicenter study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To evaluate the real‐world effectiveness, safety, and treatment retention of cenobamate (CNB) in patients with drug‐resistant epilepsy (DRE), including ultra‐refractory epilepsy (URE), high seizure burden, and extensive prior treatment history.
Ondřej Strýček   +9 more
wiley   +1 more source

Multi‐Hazard Shaking‐Tsunami Fatality Risk Estimation for Coastal Communities

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT This study develops a multi‐hazard fatality risk model for a coastal community (Tofino) on Vancouver Island, Canada, subjected to earthquake‐tsunami threats from the Cascadia subduction megathrust events. The model incorporates variable population distributions and uncertain fatality rate models, in addition to other key model components, such
Katsuichiro Goda
wiley   +1 more source

Towards a Unified Research Agenda: International Consensus to Advance Understanding and Prevention of Sudden Unexpected Death in Epilepsy. [PDF]

open access: yesEpilepsy Curr
Pickard H   +9 more
europepmc   +1 more source

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