Results 71 to 80 of about 3,214,196 (307)

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Sudden cardiac death

Journal of the Practice of Cardiovascular Sciences, 2015
Sudden cardiac death is one of the most common cause of mortality worldwide. Despite significant advances in the medical science, there is little improvement in the sudden cardiac death related mortality.
Neeraj Parakh
doaj   +3 more sources

Incidence and Etiology of Sudden Cardiac Death: New Updates for Athletic Departments

Sports health, 2017
Context: Sudden cardiac death (SCD) in a young athlete is a tragic event and is the leading medical cause of death in this population. The precise incidence of SCD in young athletes has been subject of debate, with studies reporting drastically different
I. Asif, K. Harmon
semanticscholar   +1 more source

Chelation‐Driven Dual‐Interface Regulation for Long‐Life Aqueous Zn–I2 Batteries

Advanced Science, EarlyView.
Zn2+–TPEN coordination generates TPEN‐derived coordination species (TCC) that contribute to the regulation of both electrode interfaces. At the Zn anode, it creates an interfacial environment with reduced water accessibility that suppresses HER and corrosion while promoting uniform deposition; at the I2 cathode, it captures polyiodide to inhibit ...
Dong Wook Kim, Seung Hwa Park, Tae Rim Kim, Gun Jang, Jun Su Kim, Myung‐Jun Kwak, Seokhwan Jin, Seongbin Ga, Chihyun Hwang, Ho Seok Park, Youngkwon Kim   +10 more
wiley   +1 more source

Modifier genes for sudden cardiac death

European Heart Journal, 2018
Genetic conditions, even those associated with identical gene mutations, can present with variable clinical manifestations. One widely accepted explanation for this phenomenon is the existence of genetic factors capable of modifying the consequences of ...
P. Schwartz, L. Crotti, A. George
semanticscholar   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Towards Better Understanding of the Pathogenesis of Neuronal Respiratory Network in Sudden Perinatal Death

Frontiers in Neurology, 2017
Sudden perinatal death that includes the victims of sudden infant death syndrome, sudden intrauterine death syndrome, and stillbirth are heartbreaking events in the life of parents.
Riffat Mehboob, Riffat Mehboob, Mahvish Kabir, Naseer Ahmed, Naseer Ahmed, Fridoon Jawad Ahmad   +5 more
doaj   +1 more source

2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death.

European Heart Journal, 2022
K. Zeppenfeld, J. Tfelt-Hansen, M. de Riva, B. Winkel, E. Behr, N. Blom, P. Charron, D. Corrado, N. Dagres, C. de Chillou, L. Eckardt, T. Friede, K. Haugaa, M. Hocini, P. Lambiase, É. Marijon, Jose L. Merino, P. Peichl, S. Priori, T. Reichlin, J. Schulz-Menger, C. Sticherling, S. Tzeis, Axel Verstrael, M. Volterrani   +24 more
semanticscholar   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Appropriate time interval to update ambiguous genetic diagnosis in inherited arrhythmogenic syndromes

iScience
Summary: Genetic analysis identified the cause of the disease in inherited arrhythmogenic syndromes. A clinically actionable genetic diagnosis requires an accurate interpretation following the current guidelines. Practically half of the genetic diagnoses
Estefanía Martínez-Barrios, Andrea Greco, Sergi Cesar, Carles Díez-López, José Cruzalegui, Nuria Díez-Escuté, Patricia Cerralbo, Fredy Chipa, Irene Zschaeck, Simone Grassi, Antonio Oliva, Norma Balderrábano, Rocío Toro, Georgia Sarquella-Brugada, Oscar Campuzano   +14 more
doaj   +1 more source