Results 111 to 120 of about 2,807,341 (362)

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo   +9 more
wiley   +1 more source

Morbidity burden and community-based palliative care are associated with rates of hospital use by people with schizophrenia in the last year of life: A population-based matched cohort study [PDF]

open access: yes, 2018
Objective: People with schizophrenia face an increased risk of premature death from chronic diseases and injury. This study describes the trajectory of acute care health service use in the last year of life for people with schizophrenia and how this ...
Arendts, Glenn   +4 more
core   +5 more sources

Amplifying Anti‐Tumor Immune Responses via Mitochondria‐Targeting Near‐Infrared Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
Interfacial Nd3+‐triplet energy transfer enables direct activation of molecular triplets under near‐infrared (NIR) irradiation for reactive oxygen species (ROS) generation. Photodynamic therapy (PDT) exaggerates hypoxia, which initiates subsequent hypoxia‐activated chemotherapy.
Cheng‐Ao Li   +13 more
wiley   +1 more source

Book review: Egzamin na tłumacza przysięgłego. Tłumaczenie odpisów aktów stanu cywilnego. Język francuski [The Sworn Translator Examination: translation of excerpts from Civil Status Records in the French Language]

open access: yesJęzykoznawstwo
The book Egzamin na tłumacza przysięgłego. Tłumaczenie odpisów aktów stanu cywilnego. Język francuski [The Sworn Translator Examination: Translation of Excerpts from Civil Status Records in the French Language] explores practical aspects of legal ...
Maksymilian Bartoszewski
doaj   +1 more source

A reproducible approach with R markdown to automatic classification of medical certificates in French [PDF]

open access: yes, 2017
In this paper, we report the ongoing developments of our first participation to the Cross-Language Evaluation Forum (CLEF) eHealth Task 1: “Multilingual Information Extraction - ICD10 coding” (Névéol et al., 2017).
Beghini, Federica   +3 more
core   +2 more sources

A Nano‐Electro‐Platform Enabling Evolutionary Screening and Remodeling of Tumor Cells for Metastasis Inhibition

open access: yesAdvanced Science, EarlyView.
The nano‐electro‐platform achieves non‐destructive evolutionary screening and electro‐remodeling of tumor cells to generate extracellular vesicles with enhanced tumor‐targeting and therapeutic functions. These extracellular vesicles demonstrate remarkable efficacy in activating both macrophages and T cells, thereby orchestrating a potent immune ...
Feng Liu   +20 more
wiley   +1 more source

Analýza faktorů asociovaných s vícečetnými příčinami smrti v Česku v roce 2018 pomocí XGBoost regrese a metody SHAP

open access: yesDemografie
This study focuses on the factors that are associated with recording multiple causes as the cause of death in Czechia. An XGBoost multiple regression is used in the analysis and its results are interpreted with SHAP values.
Bety Ukolova, Boris Burcin
doaj   +1 more source

Genetically Predicted 1400 Blood Metabolites in Relation to Risk of Prostate Cancer: A Mendelian Randomization Study

open access: yesAGING MEDICINE, EarlyView.
This study employed Mendelian Randomization to assess 1,400 blood metabolites and found a significant inverse association between the glycine‐to‐serine ratio and prostate cancer risk, suggesting a potential causal relationship. ABSTRACT Objectives Metabolic dysregulation is common in cancer, yet evidence linking circulating metabolites to causal ...
Xiaojin Lu   +8 more
wiley   +1 more source

Factors Associated With Frailty Clinic Utilization by High‐Need High‐Risk Older Adult Veterans

open access: yesAGING MEDICINE, EarlyView.
Clinical models incorporating assessments and interventions in the physical, functional, psychological, and social domains may be helpful for older adults with frailty and other higher‐risk geriatric patients. However, patient participation in these clinical programs is variable.
Marianne Desir   +3 more
wiley   +1 more source

Accuracy of death certificate completion: the need for formalized physician training.

open access: yesJournal of the American Medical Association (JAMA), 1996
OBJECTIVE To assess the extent to which accuracy of death certificate completion varies with level of physician training and experience. DESIGN AND SETTING In a classroom setting, subjects were presented with six written cases of hospital deaths ...
J. Messite, S. Stellman
semanticscholar   +1 more source

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