Results 231 to 240 of about 414,486 (293)

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

iMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji, Haochen Li, Qi Wang, Xiaojuan Wang, Jiawei Zhang, Ying Xiao, Huan Li, Hao Liu, Tanqing Long, Boyang Wu, Hao Chen, Haoming Xia, Xinquan Liu, Chuanrui Xu, Yibo Gao, Bingjun Tang, Juan Liu, Shizhong Yang, Jiahong Dong   +18 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

“Enshrined in Golden Memories” Eastern Ontario’s Commemoration of the North-West Resistance, 1885-1939 [PDF]

, 2015
Elliot Worsfold
core   +1 more source

Looking Within: Self‐Concept, Cognitive Flexibility, and Emotion Regulation as Intrapersonal Discriminants of Non‐Suicidal Self‐Injury Cessation

Journal of Clinical Psychology, EarlyView.
ABSTRACT Background Given their modifiable nature, understanding the intrapersonal factors involved in the cessation of non‐suicidal self‐injury (NSSI) is needed to inform existing therapeutic approaches and explore novel avenues for supporting individuals with NSSI.
Caitlyn Herrick, Glenn Melvin, David Skvarc, Helen Mildred   +3 more
wiley   +1 more source

Cohort profile: The Halmstad University Register on Pupils with Intellectual Disability

JCPP Advances, EarlyView.
Abstract Background Knowledge about the living conditions among people with intellectual disabilities (ID) is globally scarce. Even in countries with good access to registers, this is often partly due to the absence of a single, comprehensive, nationwide register of individuals with ID or the inability to identify all individuals with ID within ...
Eva Jönsson, Carin Staland‐Nyman, Paul Lichtenstein, Magnus Tideman   +3 more
wiley   +1 more source

Diagnostic value of death certificates for case ascertainment of dementia: A population-based assessment of mortality registry data. [PDF]

J Alzheimers Dis
Wolters FJ, Harteloh PPM, van Rooij FJA, Bakx P, van Heemst J, Kieboom BCT, Ikram MA.   +6 more
europepmc   +1 more source

Webster Central School District and Webster Central School Association of Educational Office Professionals (1999) [PDF]

, 1999

core   +1 more source

Decision‐making and risk‐taking as predictors of health risk behaviors in the Millennium Cohort Study

JCPP Advances, EarlyView.
Abstract Background Facets of decision‐making and risk‐taking are implicated in adolescent health risk behaviors; however, whether they may lead to adolescent engagement in substance use, gambling, and self‐harm is unknown. Methods We used the Millennium Cohort Study to test whether a task‐based measure of decision‐making and risk‐taking predicts ...
Nicole G. Hammond, Georgia Condran, Elise E. DeVito, Marie‐Claude Geoffroy, Ian Colman   +4 more
wiley   +1 more source

Screening for cardiac conditions associated with sudden cardiac death in the young : external review against programme appraisal criteria for the UK National Screening Committee [PDF]

, 2019
Bradlow, William, Clarke, Aileen, Couper, Keith, Field, Richard A., Perkins, Gavin D., Poole, Kurtis, Royle, Pamela, Taylor-Phillips, Sian, Yeung, Joyce   +8 more
core