Results 41 to 50 of about 407,809 (349)
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Causes of death in Tonga: quality of certification and implications for statistics
Population Health Metrics, 2012 Background Detailed cause of death data by age group and sex are critical to identify key public health issues and target interventions appropriately. In this study the quality of local routinely collected cause of death data from medical certification ...
Carter Karen +6 more
doaj +1 more source
Medical certification of cause of death during COVID-19 pandemic – a challenging scenario
Journal of Family Medicine and Primary Care, 2020 Death certificate data is used to monitor local, regional and national mortality trend and is helpful in improving public health as well as public safety.
Deepak Juyal +5 more
doaj +1 more source
Children’s death survey using death certificates in the Chiba prefecture
Forensic Science International: Reports, 2021 In recent years, Child Death Review (CDR) has attracted attention in Japan. It is necessary to consider not only hospital deaths but also out-of-hospital deaths.
Shumari Urabe +6 more
doaj +1 more source
Accuracy of death certification [PDF]
British Journal of Psychiatry, 2011 The death certificate allows underlying conditions leading to the cause of death, as well as other significant conditions unrelated to the immediate cause of death, to be listed. Perusal of statistics of the causes of death is instructive. The list of drugs in the Office for National Statistics’
openaire +3 more sources
Completing the Revised Death Certificate, [PDF]
, 2011 The Iowa Office of the State Medical Examiner (IOSME) has received many questions regarding completion of the revised death certificate.
core
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Uncertainties in death certification [PDF]
British Journal of General Practice, 2012 Death is one of life’s few certainties, and most GPs will inevitably preside over a few patient deaths each year. Indeed, the apotheosis of the ‘good death’ could be the patient who dies at home, dignified and pain-free following well-coordinated interdisciplinary palliative care.1 Given that around three-quarters of people express a wish to die at ...
Simon Minkoff, Edin Lakasing
openaire +3 more sources
Primary Care to the Rescue, Again! Autopsy and the Death Certificate [PDF]
, 2017 An pre and post testing, an educational module, a presentation, and a dot phrase were developed to improve providers\u27 knowledge of the hospital autopsy and the correct completion of death certificates.https://scholarworks.uvm.edu/fmclerk/1317 ...
Ryan, Emily E
core +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source