Results 21 to 30 of about 244,299 (237)
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Comparing strategies for United States veterans' mortality ascertainment [PDF]
, 2005 BACKGROUND: We aimed to determine optimal strategies for complete mortality ascertainment comparing death certificates and United States (US) Veterans Administration (VA) records. METHODS: We constructed a cohort of California veterans who died in fiscal
Asch, Steven M +4 more
core +3 more sources
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Calidad del llenado del certificado de defunción y muerte fetal en un hospital de segundo nivel en México [PDF]
, 2014 l os certificados de defunción y muerte fetal son de valor legal, epidemiológico y es tadístico, el objetivo del presente estudio es proponer un modelo objetivo y evaluar la calidad del llenado en un hospital de segundo nivel en México.
Henández Mier, C.
core
Medical Certificates of Death: First Principles and Established Practices Provide Answers to New Questions [PDF]
, 2016 Voluntary euthanasia became legal in Quebec in December 2015,1 although the legislation is currently the subject of litigation. In addition, physician-assisted death will become legal across Canada in February 2016, barring an extension on the deadline ...
Downie, Jocelyn, Oliver, Kacie
core +2 more sources
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Under Reporting of Dementia Deaths on Death Certificates: A Systematic Review of Population-based Cohort Studies [PDF]
, 2014 The purpose of this review is to assess the extent to which dementia is omitted as a cause of death from the death certificates of patients with dementia.
Benito Léon, Julián +2 more
core +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source