Results 91 to 100 of about 1,987,954 (258)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Preventable Trauma Death Rate in South Korea. [PDF]

Korean J Neurotrauma, 2023
Jung IH, Yun JH, Lee SK.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis the Impact of COVID-19 Vaccine Doses on Daily Cases, Deaths, and Recoveries: A Statistical Analysis of Turkish Public Data

Ahi Evran Medical Journal
Purpose: The COVID-19 epidemic has affected the entire world. This article aims to investigate the relationship between daily COVID-19 cases, deaths and recoveries, and daily COVID-19 vaccines in Turkey, and the effectiveness of vaccine studies ...
Ebru Uğraş, Erhan Şimşek
doaj   +1 more source

Response of a three-species cyclic ecosystem to a short-lived elevation of death rate. [PDF]

Sci Rep, 2023
Chatterjee S, De R, Hens C, Dana SK, Kapitaniak T, Bhattacharyya S.   +5 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Evaluating trends and influencing factors of cardiovascular disease mortality over time: a time series analysis in West Azerbaijan province [PDF]

Health Science Monitor
Background & Aims: Cardiovascular diseases are among the most important causes of death worldwide. The present study aimed to evaluate the trend of changes in the death rate due to cardiovascular diseases, with an emphasis on short- and long-term ...
Javad Rasouli, Arzoo Hosseini, Vahid Alinejad   +2 more
doaj  

Future world cancer death rate prediction. [PDF]

Sci Rep, 2023
Gaidai O, Yan P, Xing Y.
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source