Results 61 to 70 of about 16,408,492 (298)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Heart rate variability as predictive factor for sudden cardiac death

Aging, 2018
Sudden cardiac death (SCD) represents about 25% of deaths in clinical cardiology. The identification of risk factors for SCD is the philosopher's stone of cardiology and the identification of non-invasive markers of risk of SCD remains one of the most ...
F. Sessa, V. Anna, G. Messina, G. Cibelli, V. Monda, G. Marsala, M. Ruberto, A. Biondi, Orazio Cascio, G. Bertozzi, D. Pisanelli, F. Maglietta, A. Messina, M. Mollica, M. Salerno   +14 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Exploring the ‘fit for work’ principle: The association between occupational physical activity, cardio-respiratory fitness, and mortality – a meta-analysis of male worker data

Scandinavian Journal of Work, Environment & Health
OBJECTIVES: This individual participant data meta-analysis investigates the association between occupational physical activity (OPA) and both cardiovascular mortality and all-cause mortality across different cardio-respiratory fitness (CRF) groups among ...
Margo Ketels, Bart Cillekens, Els Clays, Maaike A Huysmans, Dirk De Bacquer, Andreas Holtermann, Richard P Troiano, Paul Jarle Mork, Steinar Krokstad, Henry Völzke, Marcus Dörr, Martin Bahls, Till Ittermann, Johan Clausen, Magnus T Jensen, Jussi Kauhanen, Ari Voutilainen, Miriam Wanner, Matthias Bopp, Willem van Mechelen, Allard J van der Beek, Pieter Coenen   +21 more
doaj   +1 more source

ДЛИТЕЛЬНАЯ ИММОБИЛИЗАЦИЯ — НЕИЗУЧЕННАЯ РЕАЛЬНОСТЬ. ЧАСТЬ 1

Архивъ внутренней медицины, 2012
The article is dedicated to prolonged immobilization. Currently there is no common term, definition what is a prolongedimmobilization of patients, there is no tactic to manage such patients.
А. Л. Вёрткин, В. А. Шевцова, А. А. Сокол   +2 more
doaj   +1 more source

Saudi Arabia stands as one of the leading countries for COVID-19 containment

Journal of Nature and Science of Medicine, 2020
Objective: Coronavirus disease 2019 (COVID-19) has emerged in China at the end of the year 2019 and a few weeks later it has out broken globally. There are obvious geographical variations in the mortality rates of COVID-19 according to the data published
Fadilah Sfouq Aleanizy, Fulwah Yahya Alqahtani, Jouri Alanazi, Hajar AlQahtani, Marzouqah Alanazi   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

COVID-19 in Relation to Polypharmacy and Immunization (2020–2024)

Viruses
Background: Observational studies reported worse COVID-19 evolution in relation to polypharmacy and reductions in COVID-19 hospital admissions and death in patients receiving chronic antihistamine treatment.
Anna Puigdellívol-Sánchez, Marta Juanes-González, Ana Calderón-Valdiviezo, Roger Valls-Foix, Marta González-Salvador, Celia Lozano-Paz, Josep Vidal-Alaball   +6 more
doaj   +1 more source