Physician reports of medication use with explicit intention of hastening the end of life in the absence of explicit patient request in general practice in Belgium [PDF]
, 2010 Background: Although the incidence of the use of life-ending drugs without explicit patient request has been estimated in several studies, in-depth empirical research on this controversial practice is nonexistent.
Meeussen, Koen +5 more
core +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Myanmar mortality registration: an assessment for system improvement
Population Health Metrics, 2017 Background The vital registration system in Myanmar has a long history and geographical coverage is currently high. However, a recent assessment of vital registration systems of 148 countries showed poor performance of the death registration system in ...
Myitzu Tin Oung +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Insight ToolKit Image Registration Framework
Frontiers in Neuroinformatics, 2014 Publicly available scientific resources help establish evaluation standards, provide a platform for teaching and improve reproducibility. Version 4 of the Insight ToolKit ( ITK4 ) seeks to es- tablish new standards in publicly available image ...
Brian eAvants +5 more
doaj +1 more source
Data quality monitoring and performance metrics of a prospective, population-based observational study of maternal and newborn health in low resource settings [PDF]
, 2015 BACKGROUND: To describe quantitative data quality monitoring and performance metrics adopted by the Global Network´s (GN) Maternal Newborn Health Registry (MNHR), a maternal and perinatal population-based registry (MPPBR) based in low and middle income ...
Althabe, Fernando +23 more
core +3 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Increasing the Scope of Birth and Death Registration: Issues and Challenges
Jurnal Bina Praja, 2016 Despite being regulated by the Presidential Decree No 25 of 2008, which then was simplified by the Law No 24 of 2013, the registration of birth and death in Indonesia does not automatically promote the scope of birth and death certificate in Indonesia ...
Hari Prasetyo, Moh. Ilham A. Hamudy
doaj +1 more source
cancer Incidence and Mortality in Ardabil: Report of an Ongoing Population-Based Cancer Registry in Iran, 2004-2006 [PDF]
Background: Ardabil cancer registry is the first population-based cancer registry in Iran that was established in 2000. The first report from this registry revealed that Ardabil has one of the highest rate of gastric cardia cancer and the lowest rate of ...
بابایی, مسعود +12 more
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