Results 41 to 50 of about 4,558,771 (294)

Manifiesto de Historia a Debate.

open access: yesDiálogos, 2011
Después de ocho años de contactos, reflexiones y debates, a través de congresos, encuestas y últimamente Internet, hemos sentido la urgencia de explicitar y actualizar nuestra posición en diálogo crítico con otras corrientes historiográficas, asimismo ...
Historia a Debate
doaj   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Who Is a Journalist and Why Does it Matter? Disentangling the Legal and Ethical Arguments [PDF]

open access: yes, 2007
The contemporary debate about who is a journalist is occurring in two distinct domains: law and professional ethics. Although the debate in these domains is focused on separate problems, participants treat the central question as essentially the same ...
Henderson, Jennifer, Ugland, Erik
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

It’s More than Just Debating: The Political Participation and Democratic Attitudes of Debate Programme Participants in Seven “New” Democracies

open access: yesSociální studia, 2019
This study is focused on the democratic competencies and political participation of young people taking part in debate programs in seven “new” democracies – the Czech Republic, Estonia, Latvia, Lithuania, Macedonia, Romania and Slovakia.
Anne Valkering   +3 more
doaj  

Too big to fail: the transatlantic debate [PDF]

open access: yes
Although the United States and the European Union were bothseriously impacted by the financial crisis of 2007, the resulting policy debates and regulatory responses have differed considerably on the two sides of the Atlantic.
Morris Goldstein, Nicolas Véron
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Diretrizes para autores

open access: yesSustentabilidade em Debate, 2013
A revista Sustentabilidade em Debate (SeD), de caráter interdisciplinar, divulga textos sobre a sustentabilidade em suas diversas dimensões, com o objetivo de criar um canal direto de debate sobre temas ligados ao desenvolvimento sustentável, gestão ...
Sustentabilidade em Debate
doaj   +2 more sources

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