Results 81 to 90 of about 4,620,189 (297)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Donors Double Down In Gaming Debate [PDF]
, 2009 On the final day of the 2009 legislative session, Florida lawmakers passed a law to expand gambling in the state and offer a new gambling compact to the Seminole Tribe, overcoming a legislature which has "resist[ed] gambling expansion for decades." The ...
Tyler Evilsizer
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Medicare, Medicaid and the Deficit Debate [PDF]
, 2012 Examines 2000-10 Medicare and Medicaid expenditures; projections for 2011-20 from the Centers for Medicare and Medicaid Services and the Congressional Budget Office; contributing factors, including enrollment growth; and proposals for curbing ...
John Holahan, Stacey McMorrow
core
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The IAM 100 Model : A Debate [PDF]
, 1984 [Excerpt] The last issue of Labor Research Review was devoted to what we called the IAM District 100 model for fighting concessions. Six articles over more than 90 pages explained the complex and sophisticated campaign the Machinists waged at Eastern ...
Metzgar, Jack
core +1 more source