Results 41 to 50 of about 109,521 (261)
This article describes a pedagogical proposal, based on debates, to determine the type of arguments that pre-service English language teachers constructed at a public university in Tunja, Colombia.
Ángela Vanesa Duarte Infante +2 more
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
La politique en embuscade : trois débats autour de l’œuvre autonome et ses effets
In contrast to the theory of art for art’s sake, which posits the fundamentally apolitical nature of art, the idea that the autonomy of the works must always be considered from a political perspective has been defended by art historians since the 18th ...
Jean-Philippe Uzel
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Japón presente y ausente en las Historias
Este artículo propone transitar la relectura de una generación de textos académicos que a nivel internacional y nacional desde los ochenta a esta parte, constituyen un canon bibliográfico con el cual se suele abordar la Historia (del Diseño Industrial ...
Luis San Filippo
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conversaciones entre Deodoro y Paulo
Uno de los principales críticos que ha formado una escuela de pensamiento y acción en torno a una reforma educativa en Latinoamérica ha sido el brasilero Paulo Freire, que mediando el siglo XX, ofrece a América Latina una visión nueva y superadora de las
Gabriela Rotondi
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Este escrito editorial tiene por objetivo reflexionar sobre la necesidad disciplinar de abordar las Relaciones Internacionales, RR. II., desde una perspectiva local.
Carlos Hernán González Parias
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

